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LAIR1抗体LAIR1兔多抗抗体Leukocyte-ass

ociated immunoglobulin-like receptor 1 antibody抗体LAIR1 Antibody, HRP conjugated抗体
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  • ¥880 - 1320
  • CUSABIO已认证
  • CN
  • CSB-PA012721LB01HU
  • 2025年07月13日
  • ELISA
  • Rabbit
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      Recombinant Human Leukocyte-associated immunoglobulin-like receptor 1 protein (22-165AA)

    • 亚型

      IgG

    • 形态

      Liquid

    • 保存条件

      Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.

    • 克隆性

      Polyclonal

    • 标记物

      HRP

    • 适应物种

      Human

    • 保质期

      6个月

    • 抗原来源

      Homo sapiens (Human)

    • 目录编号

      Q6GTX8

    • 级别

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 宿主

      Rabbit

    • 应用范围

      ELISA

    • 浓度

      >95%,Protein G purified

    • 靶点

      LAIR1

    • 抗体英文名

      LAIR1 Antibody, HRP conjugated

    • 抗体名

      Leukocyte-associated immunoglobulin-like receptor 1 antibody

    • 规格

      100μg/50μg

    规格:100μg产品价格:¥1320.0
    规格:50μg产品价格:¥880.0

    保存缓冲液

    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

    功能

    Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta. Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion. Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells. Inhibits the differentiation of peripheral blood precursors towards dendritic cells.

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    • CD11a/CD11b/CD11c分子

      associated alpha and beta subunits   CD11a Aka alpha L; LFA-1 (in complex with CD18) An alpha integrin chain that binds to CD18 and mediates leukocyte adhesion and lymphocyte recirculation through lymph

    • (共享)免疫单词缩写及翻译

      缩写 全称 中文 AA autoantibody 自身抗体 AAF aminoacetylfluorescence 氨乙酰基荧光 Ab antibody 抗体 ABC avidin-biotin peroxidase complex 抗生物素(亲合素)-生物素-过氧化物酶复合物 ACh acetycholine 乙酰胆碱 AChR acetycholine receptor 乙酰胆碱受体 AChRAb acetycholine

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    文献支持
    LAIR1抗体LAIR1兔多抗抗体Leukocyte-associated immunoglobulin-like receptor 1 antibody抗体LAIR1 Antibody, HRP conjugated抗体
    ¥880 - 1320