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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide sequence around aa.210~214 (S-R-T-P-S) derived from Human Tau.
- 亚型:
/
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
/
- 适应物种:
Human,Mouse,Rat
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P10636
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB;WB:1:500-1:1000
- 浓度:
>95%,Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 靶点:
MAPT
- 抗体英文名:
MAPT (Ab-212) Antibody
- 抗体名:
/
- 规格:
100μl
保存缓冲液
/功能
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Gong CX, et al. (2006) J Biomed Biotechnol. 2006: 31825
Zheng-Fischhofer Q, et al. (1998) Eur J Biochem. 252:542
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文献和实验
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