- ￥2024
- CUSABIO
- CN
- CSB-PA445446
- 2025年07月08日
- ELISA,WB;WB:1:500-1:1000
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Peptide sequence around aa. 44~48 (M-L-S-P-D) derived from Human p53.
- 亚型：
/
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
/
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
P04637
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB;WB:1:500-1:1000
- 浓度：
>95%,Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 靶点：
TP53
- 抗体英文名：
TP53 (Ab-46) Antibody
- 抗体名：
/
- 规格：
100μl
保存缓冲液
/功能
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over.Dhavan, R. and Tsai, L.H. (2001) Nat Rev Mol Cell Biol. 2: 749-759.
Patrick, G. N. et al. (1998) J Biol Chem. 273: 24057-24064.
Di Stefano V, et al. (2005) Oncogene. 24(35):5431-5442.
Mayo LD, et al.(2005) J Biol Chem. 280(28):25953-25959.
Wang L, et al. (2005) Oncogene. 24(18): 3020-3027.
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TP53抗体TP53兔多抗抗体/抗体TP53 (Ab-46) Antibody抗体
￥2024
