- ￥2024
- CUSABIO
- CN
- CSB-PA994602
- 2025年07月16日
- ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100
- Rabbit
- Human,Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthesized non-phosphopeptide derived from Human DAPK3 around the phosphorylation site of threonine 265 (R-M-T(p)-I-A).
- 亚型：
/
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
/
- 适应物种：
Human,Mouse
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O43293
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA,WB,IHC;WB:1:500-1:3000,IHC:1:50-1:100
- 浓度：
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点：
DAPK3
- 抗体英文名：
DAPK3 (Ab-265) Antibody
- 抗体名：
/
- 规格：
100μl
保存缓冲液
/功能
Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation, actin cytoskeleton reorganization, cell motility, smooth muscle contraction, and mitosis, particularly cytokinesis. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of PPP1R12A, and the inhibition of SMPP1M functions to enhance muscle responsiveness to Ca2+ and promote a contractile state. Enhances transcription from AR-responsive promoters in a hormone- and kinase-dependent manner. Phosphorylates STAT3 and enhances its transcriptional activity. Positively regulates the canonical Wnt/beta-catenin signaling through interaction with NLK and TCF7L2. Can disrupt the NLK-TCF7L2 complex thereby influencing the phosphorylation of TCF7L2 by NLK. Phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. Involved in the formation of promyelocytic leukemia protein nuclear body (PML-NB), one of many subnuclear domains in the eukaryotic cell nucleus, and which is involved in oncogenesis and viral infection. Phosphorylates RPL13A on 'Ser-77' upon interferon-gamma activation which is causing RPL13A release from the ribosome, its association with the GAIT complex and its subsequent involvement in transcript-selective translation inhibition. Isoform 2 can phosphorylate myosin, PPP1R12A and MYL12B.Kawai T., Mol. Cell. Biol. 18:1642-1651(1998).
Murata-Hori M., FEBS Lett. 451:81-84(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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文献和实验dongreyuan 有的抗体名称上面写着Ab-33，比如，β-catenin（Ab-33）antibody，请问，Ab-33是什么意思？ bettyzyj 这个抗体是非磷酸化的抗体non-phospho-antibody ，33 代表的是基因位点 dongreyuan 谢谢了 yhwangcams bettyzyj wrote
AB0系统的抗体是检验主管技师考试的内容，医学教育网搜集整理相关内容供大家参考。 天然抗体与免疫性抗体：天然抗体是在没有可觉察的抗原刺激下而产生的抗体，以IgM为主，又称完全抗体或盐水抗体；也可能是由一种无觉察的免疫刺激产生而得。免疫性抗体：有IgM、IgG、IgA，但主要是IgG.抗A和抗B可以是IgM与IgG，甚至是IgM、IgG、IgA的混合物，但主要是IgM，而0型血清中以IgG为主。
Production of Bispecif ic and Trispecific F(ab)2 and F(ab)3 Antibody Derivatives
Bispecific antibodies (BsAbs) are hybrid molecules designed to combine two antibodies with different specificities. This dual specificity has led to their application in a variety of diagnostic situations that require the crosslinking
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