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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Peptide sequence around aa.127~131 (I-L-S-R-R) derived from Human CREB.
- 亚型:
/
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
/
- 适应物种:
Human,Mouse,Rat
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P16220
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC;WB:1:500-1:1000,IHC:1:50-1:200
- 浓度:
>95%,Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- 靶点:
CREB1
- 抗体英文名:
CREB1 (Ab-129) Antibody
- 抗体名:
/
- 规格:
100μl
保存缓冲液
/功能
CREB1 is a transcription factor that is a member of the bZIP family of DNA binding proteins. It binds as a homodimer to the CRE (cAMP-Responsive Element), an octameric palindrome containing a conserved core sequence, 5-prime-TGACG-3-prime. It consists of two transcript variants encoding respective isoforms produced by alternate splicing. It is mapped to 2q32.3-q34 . It is phosphorylated by several protein kinases and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB1 is crucial for the consolidation of long-term conditioned fear memories, but not for encoding, storage, or retrieval of these memories. It is required for the stability of reactivated or retrieved conditioned fear memories .Chrystelle V. Garat, et al. (2006) Mol. Cell. Biol ; 26: 4934 - 4948.
Lilah Rothem,et al. (2004) Mol. Pharmacol ; 66: 1536 - 1543.
Darren R. Tyson, et,al. (2002) Endocrinology; 143: 674.
Kyung-Woo Park, et al. (2003) Arterioscler. Thromb. Vasc. Biol ; 23: 1364.
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文献和实验dongreyuan 有的抗体名称上面写着Ab-33,比如,β-catenin(Ab-33)antibody,请问,Ab-33是什么意思? bettyzyj 这个抗体是非磷酸化的抗体non-phospho-antibody ,33 代表的是基因位点 dongreyuan 谢谢了 yhwangcams bettyzyj wrote
AB0系统的抗体是检验主管技师考试的内容,医学教育网搜集整理相关内容供大家参考。 天然抗体与免疫性抗体:天然抗体是在没有可觉察的抗原刺激下而产生的抗体,以IgM为主,又称完全抗体或盐水抗体;也可能是由一种无觉察的免疫刺激产生而得。免疫性抗体:有IgM、IgG、IgA,但主要是IgG.抗A和抗B可以是IgM与IgG,甚至是IgM、IgG、IgA的混合物,但主要是IgM,而0型血清中以IgG为主。
Production of Bispecif ic and Trispecific F(ab)2 and F(ab)3 Antibody Derivatives
Bispecific antibodies (BsAbs) are hybrid molecules designed to combine two antibodies with different specificities. This dual specificity has led to their application in a variety of diagnostic situations that require the crosslinking
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