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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant protein of Human LTA
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
/
- 适应物种:
Human,Mouse,Rat
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P01374
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
ELISA,WB,IHC;WB:1:500-1:2000,IHC:1:50-1:200
- 浓度:
>95%,Affinity purification
- 靶点:
LTA
- 抗体英文名:
LTA Antibody
- 抗体名:
tumor necrosis factor superfamily member 1 antibody
- 规格:
100μl
保存缓冲液
Store at -20oC or -80oC. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.功能
Lymphotoxin-α (LT-α), also known as TNF–β, is a member of the TNF superfamily of proteins. NK cells, T cells, B cells, and lymphoid tissue-inducer cells express LT-α. LT-α can be secreted as a soluble homotrimer or form membrane bound heterotrimers with lymphotoxin-β (LT α1β2 or LT α2β1) which can be cleaved from the cell surface by matrix metalloproteases. Soluble LT-α binds to and signals through TNFR1/TNFR2, activating the canonical NF-κB pathway. In contrast, LT α1β2 heterodimers bind to the LTβR receptor and activate the noncanonical NF-κB pathway. As a result, LT-α and TNF-α have overlapping functions. Soluble LT-α and LT α1β2 play key roles in lymphangiogenesis. The LT α1β2/LTβR axis is essential for the development of lymphoid tissue.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
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Chimerization of a Monoclonal Antibody for Treating Hodgkin's Lymphoma
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xxzjcg 急求OX40基因序列,在gene bank 里没有明确的OX40基因序列 woxingwosu 根据你的基因,我查了一下NCBI,上面有多个OX40(http://www.ncbi.nlm.nih.gov/gene?term=OX40),我列举了其中一个,TNFRSF4 tumor necrosis factor receptor superfamily, member 4 [ Homo sapiens
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