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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from Human JAK1 around the phosphorylation site of Y1022.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse,Rat
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
P23458
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
WB, IHC, ELISA; WB:1:500-1:2000, IHC:1:100-1:300, ELISA:1:10000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
JAK1
- 抗体英文名:
Phospho-JAK1 (Y1022) Antibody
- 抗体名:
Tyrosine-protein kinase JAK1 antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验Immunoprecipitation to Determine JAK Kinase Activation in Response to Interleukins in Ovarian Cancer
In cytokine receptors, there is no consensus sequence motif for tyrosine and/or serine/threonine kinases in its intracellular domain (1 ). Cytokine receptors associate with and activate members of the Janus kinase family (JAK
-transduction pathways that are downstream of each of the receptors are shown. Each of these common cytokine-receptor γ-chain (γ c)-dependent cytokine s signals through a Janus activated kinase 1 (JAK1) interaction with its corresponding cytokine-specific type
(Lymphocyte-Specific Protein Tyrosine Kinase), which is involved in T-cell receptor signaling. Signaling from the T-cell receptor does activate PLC-Gamma, but this requires ligand binding. The protein tyrosine kinases JAK1 and JAK3 (Janus Kinases
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