ARHGAP12抗体ARHGAP12一抗抗体Rho-type
GTPase-activating protein 12 antibody抗体ARHGAP12 Antibody抗体- ￥880 - 1320
- CUSABIO
- CN
- CSB-PA070306
- 2025年07月10日
- WB, ELISA; WB:1:500-1:2000, ELISA:1:40000
- Rabbit
- Human,Mouse,Rat
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Synthesized peptide derived from the Internal region of Human ARHGAP12.
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
/
- 标记物：
Non-conjugated
- 适应物种：
Human,Mouse,Rat
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
Q8IWW6
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
WB, ELISA; WB:1:500-1:2000, ELISA:1:40000
- 浓度：
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点：
ARHGAP12
- 抗体英文名：
ARHGAP12 Antibody
- 抗体名：
Rho-type GTPase-activating protein 12 antibody
- 规格：
100μg/50μg
| 规格： | 100μg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验ARF GTPase-Activating Protein 1
of intrinsic GTPase activity, and GTP hydrolysis depends on the action of GTPase-activating proteins (GAPs). ARF GAPs are a family of proteins which contain a conserved GAP domain of approx 130 amino acids with a unique Cys4 zinc-finger motif near their amino
(for reviews, see refs. 1 and 2 ). By sequence homology of G protein α-subunits, they are divided into four subfamilies, Gs , G1 , Gq , and G12 . Agonist bindmg is assumed to induce a conformational change of the receptor, which causes exchange of GDP for GTP
The GTPase Cycle How Dominant Inhibitory Mutants Block the Biological Functions of Small GTPases
the loss of protein function. This method can be introduced by genetic manipulation, anti-sense DNA/RNA, specific antibodies, drugs, or expression of so-called “dominant inhibitory” proteins. These proteins have emerged as popular tools to accomplish GTPase
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