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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthesized peptide derived from the C-terminal region of Human GHRH-R.
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
/
- 标记物:
Non-conjugated
- 适应物种:
Human,Mouse,Rat
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q02643
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
WB, IF, ELISA; WB:1:500-1:2000, IF:1:200-1:1000, ELISA:1:20000
- 浓度:
>95%,The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 靶点:
GHRHR
- 抗体英文名:
GHRHR Antibody
- 抗体名:
Growth hormone-releasing hormone receptor antibody
- 规格:
100μg/50μg
| 规格: | 100μg | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μg | 产品价格: | ¥880.0 |
保存缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.功能
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文献和实验Mammalian adaptation to stressful stimuli requires activation of the type 1 corticotropin releasing hormone (CRH) receptor (CRH-R1), a 415 aminoacid protein that belongs to the large superfamily of 7 transmembrane domain receptors that relay
激素作用于细胞时,与神经传递物质一样,第一阶段是与细胞中的特定化学物质进行特异的结合,称此化学物质为激素受体。激素受体可分为两类,一类是对类固醇激素的受体,溶存于细胞质中;另一类是肽激素的受体,存在肽激素的靶细胞的细胞膜,在膜外面有与激素结合的部位,是难溶于水的复合蛋白质,可被乙醇或表面活性剂从膜上溶出。各种肽激素均具其特有的受体。激素分子与受体分子的结合是非价键结合。另外在热力学上则称为尔刚 ( ergon)反应,不需要从外部供给能量。结合的平衡常数多为 109 M-1
Steroid Hormone Metabolites and Hormone Binding Assays
of the steroid/thyroid hormone receptor superfamily, and they act as ligand-dependent transcription factors to either activate or repress target gene expression ( 1 , 2 ). They regulate gene transcription by binding to hormone response element DNA sequences
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