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| 产品编号 | bs-0214P |
| 英文名称 | DFFA Antibody Blocking Peptide |
| 中文名称 | Caspase激活的脱氧核糖核酸酶抑制剂封闭多肽 |
| 英文别名 | DNA fragmentation factor subunit alpha; DFF-45; Inhibitor of CAD; ICAD; DFF1; DFF45; H13; DFFA; DFFA_HUMAN; |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Cell Death > Apoptosis > Metabolism Cancer > Cell Death > Apoptosis > Nucleus > DNAses Cell Biology > Apoptosis > Nucleus > DNAses Epigenetics and Nuclear Signaling > Cell cycle > Apoptosis > Nuclear Metabolism > Pathways and Processes > Metabolism processes > Apoptosis |
| 亚基 | Heterodimer of DFFA and DFFB. |
| 亚细胞定位 | Cytoplasm. |
| 翻译后修饰 | Caspase-3 cleaves DFF45 at 2 sites to generate an active factor. |
| 相似性 | Contains 1 CIDE-N domain. |
| 功能 | Inhibitor of the caspase-activated DNase (DFF40). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | Caspase-activated deoxyribonuclease(CAD) also designated DNA fragmentation factor 45 kDa subunit (DFF-45)and Caspase-activated DNase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. ICAD (DNA fragmentation factor alpha subunit) (DNA fragmentation factor 45 kDa subunit) (DFF-45) (Inhibitor of CAD) is inhibitor of the caspase-activated DNase (DFF44). |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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