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- bs-2325P
- 2025年10月17日
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500mg
| 产品编号 | bs-2325P |
| 英文名称 | Histamine |
| 中文名称 | 组织胺/组胺 |
| 英文别名 | 2-(4-Imidazolyl)ethylamine; |
| 性状 | Lyophilized |
| 研究领域 | Immunology > Innate Immunity > Macrophage / Inflamm. Immunology > Secreted Molecules > Other secreted molecules |
| 亚基 | Histamine has two basic centres, namely the aliphatic amino group and whichever nitrogen atom of the imidazole ring does not already have a proton. Under physiological conditions, the aliphatic amino group (having a pKa around 9.4) will be protonated, whereas the second nitrogen of the imidazole ring (pKa ≈ 5.8) will not be protonated. Thus, histamine is normally protonated to a singly charged cation. |
| 保存条件 | Stored at 2-8℃. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Histamine is located in mast cells, endocrine cells of the gut, blood cells and in some cells of the peripheral and central nervous system. Histamine is a potent vasodilator when secreted by mast cells found in various tissues as a result of allergic hypersensitivity or inflammation. Histamine causes running nose, sneezing and itching, and narrows the airways in the lungs. In the central nervous system, Histamine is putative neurotransmitter. In the brain, its highest content has been found in the hypothalamus and in certain areas of the mesencephalon. CAS: 51-45-6 |
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文献和实验and stored in granules. An example is histamine. Other mediators are generated de novo , e.g., eicosanoids. Mast cells and basophils produce some important cytokines, e.g., IL-4, IL-13, TNF-α (1 –5 ) and the chemokines MlP-1α and RANTES
Mast Cell Histamine and Cytokine Assays
Mast cells are crucial to the development of chronic allergic inflammation and are likely to play a critical role in host defense. In this chapter methodology for histamine and cytokine assays is provided. Crosslinkage of IgE receptor I (Fcε
Histamine N-Methyltransferase: Enzymology and Functional Aspects
Histamine N -methyltransferase (HNMT; EC 2.1.1.8) was discovered a little over 25 yr ago. Since that time, HNMT has been the subject of numerous investigations, and although these studies have provided a fundamental understanding of this enzyme
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