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- bs-17081R
- 2025年10月24日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-17081R |
| 英文名称 | KATNAL2 Rabbit pAb |
| 中文名称 | KATNAL2蛋白抗体 |
| 英文别名 | DKFZP667C165; Katanin p60 ATPase-containing subunit A-like 2; Katanin p60 subunit A like 2; Katanin p60 subunit A-like 2; KATL2_HUMAN; KATNAL 2; katnal2; MGC33211; p60 katanin like 2; p60 katanin-like 2. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KATNAL2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 61 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > DNA / Nucleotides Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP |
| 亚细胞定位 | Cytoplasm; cytoskeleton. |
| 相似性 | Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily. Contains 1 LisH domain. |
| 功能 | Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin is a heterodimer complex that severs microtubules in an ATP-dependent manner. The severing of microtubules by the Katanin complex may promote reorganization of cellular microtubule arrays and release of microtubules from the centrosome following nucleation. The Katanin complex is composed of a 60 kDa subunit (Katanin p60 A1) and a 80 kDa accessory protein (Katanin p80 B1). Katanin p60 A1 is responsible for the severing and disassembly of microtubules, while Katanin p80 B1 targets the complex to the centrosome. Katanin p60 A1 and Katanin p80 B1 belong to the AAA ATPase family, which also includes the Katanin p60 A1-like proteins, Katanin p60 AL1 and Katanin p60 AL2. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KATNAL2) Polyclonal Antibody, Unconjugated (bs-17081R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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KATNAL2 Rabbit pAb(bs-17081R)-50ul/100ul/200ul
￥1180 - 2800
