IFT46 Rabbit pAb(bs-15563R)-50ul/100ul/200ul

IFT46 Rabbit pAb(bs-15563R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-15563R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-15563R
    英文名称IFT46 Rabbit pAb
    中文名称细胞纤毛内转运同源蛋白46抗体
    英文别名C11orf2; C11orf60; IFT46; IFT46_HUMAN; Intraflagellar transport protein 46 homolog.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human IFT46
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量34 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Microtubules > MT Associated Proteins > MAP

    亚基Part of the IFT complex B. Interacts with IFT57, IFT88 and DAW1 (By similarity).
    亚细胞定位Cytoplasm, cytoskeleton, cilium basal body (By similarity). Cell projection, cilium (By similarity). Note=Expression is concentrated at the cilium basal body but is also detected along the length of the cilium (By similarity).
    相似性Belongs to the IFT46 family.
    功能Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity).
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料IFT46 is a 304 amino acid protein that belongs to the IFT46 family. IFT46 localizes to the cilium basal body but can also be found along the length of the cilium and is a part of a complex involved in intraflagellar transport (IFT). In addition, IFT46 is involved in the bi-directional movement of particles that is required for the assembly, maintenance, and functionality of primary cilia. Furthermore, IFT46 may be involved in skeletogenesis and chondrocyte maturation. Two isoforms exist due to alternate splicing events and the gene encoding IFT46 maps to human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    IFT46 Rabbit pAb(bs-15563R)-50
    Sample:
    Molt-4(Human) Cell Lysate at 30 ug
    K562(Human) Cell Lysate at 30 ug
    Primary: Anti-IFT46 (bs-15563R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 34 kD
    Observed band size: 34 kD
    IFT46 Rabbit pAb(bs-15563R)-50
    Sample:
    K562(Human) Cell Lysate at 30 ug
    Primary: Anti- IFT46 (bs-15563R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 34 kD
    Observed band size: 34 kD

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    IFT46 Rabbit pAb(bs-15563R)-50ul/100ul/200ul
    ¥1180 - 2800