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GPS2 Rabbit pAb(bs-15395R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-15395R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-15395R
    英文名称GPS2 Rabbit pAb
    中文名称G蛋白通路抑制物蛋白2抗体
    英文别名AMF-1; G protein pathway suppressor 2; GPS-2; GPS2; MGC104294; MGC119287; MGC119288; MGC119289; GPS2_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Dog, Pig, Cow, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GPS2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量37 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Cell Cycle > Cell Cycle Inhibitors > p53

    Epigenetics and Nuclear Signaling > Cell cycle > Cell Cycle Inhibitors > p53

    Epigenetics and Nuclear Signaling > Chromatin Modifying Enzymes > Acetylation > HDACs > Class I

    Epigenetics and Nuclear Signaling > DNA / RNA > DNA Damage & Repair > DNA Damage Response > p53

    Epigenetics and Nuclear Signaling > Nuclear Signaling Pathways > Nuclear Receptors > Co-activators/co-repressors

    Signal Transduction > Signaling Pathway > G Protein Signaling > Heterotrimeric G Proteins > Regulators

    Signal Transduction > Signaling Pathway > Nuclear Signaling > Nuclear Hormone Receptors > Co-activators/co-repressors

    亚基Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2.
    组织特异性Widely expressed.
    功能Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Testis (Mouse) Lysate at 40 ug
    Primary: Anti- GPS2 (bs-15395R)at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 37kD
    Observed band size: 37kD
    产品细节图片2
    Sample:
    Lane 1: Mouse Kidney tissue lysates
    Lane 2: Rat Kidney tissue lysates
    Primary: Anti-GPS2 (bs-15395R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 37 kDa
    Observed band size: 37 kDa

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    ¥1180 - 2800