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- bs-7713R
- 2025年10月16日
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产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7713R |
| 英文名称 | MIS12 Rabbit pAb |
| 中文名称 | 染色体及有丝分裂蛋白MIS12抗体 |
| 英文别名 | hMIS12; homolog of yeast Mis12; KNTC2AP; MIND kinetochore complex component, homolog(yeast); MIS12 homolog(yeast); MIS12 homolog; MIS12 MIND kinetochore complex component homolog(yeast); MTW 1; MTW1; Protein MIS12 homolog; MIS12_HUMAN. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Dog, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MIS12 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 24 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cell Division > Centromere Epigenetics and Nuclear Signaling > Cell cycle > Chromosome Structure > Centromere Epigenetics and Nuclear Signaling > Chromosome Structure > Centromeres |
| 亚基 | Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with CASC5, CBX3, CBX5, NDC80 and ZWINT. |
| 亚细胞定位 | Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore. |
| 相似性 | Belongs to the mis12 family. |
| 功能 | Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MIS12 is part of a complex that plays an essential role in chromosome segregation in vertebrates and contributes to mitotic kinetochore assembly. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
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文献和实验[IF={{ 9.6 }}] {Ogasawara, Shinyu, et al. "Cathepsin K activity controls cardiotoxin‐induced skeletal muscle repair in mice." Journal of Cachexia, Sarcopenia and Muscle (2017).} {IHC} {="Mouse"}
[IF={{ 5.443 }}] {Goto Hiroki. et al. Proliferin-1 Ameliorates Cardiotoxin-Related Skeletal Muscle Repair in Mice. Stem Cells Int. 2021;2021:9202990} {IF} {Mouse}
[IF={{ 12.511 }}] {Ogasawara et al. Cathepsin K activity controls cardiotoxin-induced skeletal muscle repair in mice. (2018) J.Cachexia.Sarcopenia.Muscle. 9:160-175} {IHC} {Mouse}
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