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KCNF1 Rabbit pAb(bs-12173R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-12173R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-12173R
    英文名称KCNF1 Rabbit pAb
    中文名称电压门控性钾通道蛋白亚基kv5.1抗体
    英文别名IK 8; IK8; KCNF 1; KCNF; Kcnf1; KCNF1_HUMAN; kH 1; kH1; KV5.1; Potassium voltage-gated channel subfamily F member 1; MGC33316; Potassium channel KH1; Potassium channel Kv5.1; Potassium voltage gated channel subfamily F member 1; Potassium voltage-gated channel subfamily F member 1; Voltage gated potassium channel subunit Kv5.1; Voltage-gated potassium channel subunit Kv5.1.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human KCNF1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量56 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Heteromultimer with KCNG3, KCNG4 and KCNV2. Interacts with DLG1.
    亚细胞定位Membrane.
    组织特异性Detected in heart, brain, liver, skeletal muscle, kidney and pancreas.
    相似性Belongs to the potassium channel family.
    F (TC 1.A.1.2) subfamily. Kv5.1/KCNF1 sub-subfamily.
    功能Putative voltage-gated potassium channel.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti- KCNF1 (bs-12173R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 56 kD
    Observed band size: 56 kD

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    该产品被引用文献

    [IF={{ 4.43 }}] {Slaats et al. Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesis. (2015) J.Cell.Sc. 128:4550-9} {IF,WB} {Mouse}

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    KCNF1 Rabbit pAb(bs-12173R)-50ul/100ul/200ul
    ¥1180 - 2800