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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-12118R |
| 英文名称 | SLC35C2 Rabbit pAb |
| 中文名称 | 溶质载体蛋白家族35成员C2抗体 |
| 英文别名 | BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 member C2. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Chicken, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human SLC35C2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 40 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚细胞定位 | Membrane. |
| 组织特异性 | Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer. |
| 相似性 | Belongs to the TPT transporter family. SLC35C subfamily. |
| 功能 | May play an important role in the cellular response to tissue hypoxia. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SLC35C2 (solute carrier family 35, member C2), also known as C20orf5, OVCOV1 or CGI-15, is a 365 amino acid multi-pass membrane protein that belongs to the TPT transporter family and exists as multiple alternatively spliced isoforms. Expressed ubiquitously and functionally induced in hypoxic trophoblast cells, SLC35C2 plays a role in the cellular response to tissue hypoxia and is thought to be involved in the pathogenesis of ovarian cancer. The gene encoding SLC35C2 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

A549 Cell (Human) Lysate at 30 ug
Primary: Anti-SLC35C2 (bs-12118R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kD
Observed band size: 40 kD

Lane 1: Mouse Liver tissue lysates
Lane 2: Mouse Cerebrum tissue lysates
Lane 3: Rat Large intestine tissue lysates
Lane 4: Rat Cerebrum tissue lysates
Primary: Anti-SLC35C2 (bs-12118R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 40 kDa
Observed band size: 48 kDa
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文献和实验= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
)测试中,其变化规律与补体的变化趋势有显著的相关性(C3、C4与IgGr=0.6683;0.6439;与IgM r=0.5805;0.6296;与IgA r=0.7569;0.9302)。表明补体水平的变化与抗体的变化直接有关。 (3)运动时内环境理化因素的改变:补体系统存在经典激活途径与旁路激活途径。补体一旦被激活后,被激活的裂解产物会产生酶样作用,依次激活下一补体,即逐步由识别阶段(C1q,C1r及C1s)过渡到效应阶段(C2、C3、C4、C5)与膜攻击阶段(C6-C9)。而由于运动中大量消耗
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