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SESN3 Rabbit pAb(bs-6100R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-6100R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-6100R
    英文名称SESN3 Rabbit pAb
    中文名称Sestrin3抗体
    英文别名SESN3; SESN3_HUMAN; SEST3; Sestrin 3; Sestrin-3.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Chicken, Dog, Pig, Cow, Horse, Rabbit, GuineaPig)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human SESN3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量54 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Tumor suppressors

    Cardiovascular > Atherosclerosis > Diabetes associated

    Cardiovascular > Hypoxia > Hypoxia-Regulated

    Cell Biology > Other Antibodies > Oxidative Stress

    Metabolism > Pathways and Processes > Redox metabolism > Oxidative stress

    亚细胞定位Widely expressed.
    相似性Belongs to the sestrin family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    U-2OS(Human) Cell Lysate at 30 ug
    Primary: Anti- SESN3 (bs-6100R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54 kD
    Observed band size: 56 kD
    产品细节图片2
    Sample:
    Cerebellum (Mouse) Lysate at 40 ug
    Cerebrum (Rat) Lysate at 40 ug
    Primary: Anti- SESN3 (bs-6100R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 54 kD
    Observed band size: 52 kD

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    该产品被引用文献

    [IF={{ 5.168 }}] {Kosaka et al. Reactive oxygen species induction by cabazitaxel through inhibiting Sestrin-3 in castration resistant prostate cancer. (2017) Oncotarget. 8:87675-87683} {ICC} {Human}

    [IF={{ 5.14 }}] {Agata Wrońska. et al. Sestrins’ Expression in the Liver Is Not Altered by Short-Term Calorie Restriction in Young and Old Rats. Gerontology. ;:1-9} {WB} {Rat}

    [IF={{ 2.5 }}] {Chen-Kai Zhang. et al.Long-term aerobic exercise enhances liver health: miRNA regulation and oxidative stress alleviation..BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2025 Mar 20:759:151677.} {Western blot} {Rat}

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    文献支持
    SESN3 Rabbit pAb(bs-6100R)-50ul/100ul/200ul
    ¥1180 - 2800