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ATG4C Rabbit pAb(bs-4008R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-4008R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-4008R
    英文名称ATG4C Rabbit pAb
    中文名称自噬相关蛋白4C抗体
    英文别名APG4 autophagy 4 homolog C(S. cerevisiae); APG4 autophagy 4 homolog C; APG4 C; APG4-C; APG4C; ATG 4C; ATG4 autophagy related 4 homolog C(S. cerevisiae); Atg4c; ATG4C_HUMAN; AUT(S. cerevisiae) like 1, cysteine endopeptidase; AUT like 1, cysteine endopeptidase(S. cerevisiae); AUT like 1, cysteine endopeptidase; AUT like 3 cysteine endopeptidase; AUT-like 3 cysteine endopeptidase; AUTL1; AUTL3; Autophagin 3; Autophagin-3; Autophagy related cysteine endopeptidase 3; Autophagy related protein 4 homolog C; Autophagy-related cysteine endopeptidase 3; Autophagy-related protein 4 homolog C; Cysteine protease ATG4C; EC 3.4.22; FLJ14867; OTTHUMP00000010715.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse, Rat (Dog, Pig, Cow, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ATG4C
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量52 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cell Death > Autophagy > APG gene products

    Cancer > Cell Death > Autophagy > Signal Transduction

    Cancer > Oncoproteins/suppressors > Oncoproteins > Cell survival & death

    Cancer > Signal transduction > Autophagy

    Cardiovascular > Heart > Autophagy > APG gene products

    Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Other proteases

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy

    Metabolism > Pathways and Processes > Metabolism processes > Autophagy and mitophagy > APG gene products

    亚细胞定位Cytoplasm (Probable).
    组织特异性Highly expressed in skeletal muscle, heart, liver and testis.
    相似性Belongs to the peptidase C54 family.
    功能Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    A673(Human) Cell Lysate at 30 ug
    Primary: Anti-ATG4C (bs-4008R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 52 kD
    Observed band size: 55 kD
    产品细节图片2
    Sample:
    Liver (Mouse) Lysate at 40 ug
    Primary: Anti-ATG4C (bs-4008R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 52 kD
    Observed band size: 55 kD
    产品细节图片3
    Sample:
    Lane 1: Mouse Muscle tissue lysates
    Lane 2: Mouse Heart tissue lysates
    Lane 3: Rat Muscle tissue lysates
    Primary: Anti-ATG4C (bs-4008R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 52 kDa
    Observed band size: 52 kDa

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    ATG4C Rabbit pAb(bs-4008R)-50ul/100ul/200ul
    ¥1180 - 2800