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C6orf25 Rabbit pAb(bs-15245R)-

50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-15245R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-15245R
    英文名称C6orf25 Rabbit pAb
    中文名称6号染色体开放阅读框25抗体
    英文别名Chromosome 6 open reading frame 25; G6b; G6B protein; Immunoglobulin receptor; MGC142279; MGC142281; NG31; Protein G6b; G6B_HUMAN.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Cow, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human C6orf25
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量24 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts with PTPN6 and PTPN11. Binds to heparin.
    亚细胞定位Isoform E: Endoplasmic reticulum. Golgi apparatus.
    Isoform D: Endoplasmic reticulum. Golgi apparatus.
    Isoform B: Cell membrane; Single-pass type I membrane protein.
    Isoform A: Cell membrane; Single-pass type I membrane protein.
    组织特异性 Expressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets.
    翻译后修饰All isoforms are N-glycosylated.
    Isoform E is O-glycosylated.
    功能Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. It is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Protein: mouse testis lysate;
    Primary: rabbit Anti-C6orf25 (bs-15245R) at 1:300;
    Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;
    Predicted band size: 24 kD
    Observed band size: 24 kD

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