- ￥1180 - 2800
- Bioss
- bs-6707R
- 2025年10月16日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6707R |
| 英文名称 | PSCD1/Cytohesin 1 Rabbit pAb |
| 中文名称 | 胞粘蛋白1抗体 |
| 英文别名 | SEC7 and coiled-coil domain-containing protein 1; B2 1; CLM1; CTH 1; CYH1_HUMAN; CYTH1; CYTIP; Cytoadhesin 1; Cytohesin-1; Homolog of secretory protein SEC7; mSec7 1; PH; PH, SEC7 and coiled-coil domain containing protein 1; Pleckstrin homology Sec7 and coiled/coil domains 1; Pleckstrin homology Sec7 and coiled/coil domains protein 1; PSCD1; Sec7; SEC7 homolog A; SEC7 homolog B2 1; SEC7 homolog B2-1; SEC7, yeast, homolog of; Sec7a. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human PSCD1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 44 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Interacts with TRIM23 and CYTIP. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Ubiquitous. |
| 相似性 | Contains 1 PH domain. Contains 1 SEC7 domain. |
| 功能 | Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF through replacement of GDP with GTP. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cytohesin 1 is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. Cytohesin 1 is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. The encoded protein is 83% homologous to that of CYTH2. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验该产品被引用文献
[IF={{ 4.192 }}] {Chaochao Luo. et al. Glutamine Regulates Cell Growth and Casein Synthesis through the CYTHs/ARFGAP1-Arf1-mTORC1 Pathway in Bovine Mammary Epithelial Cells. J Agr Food Chem. 2021;XXXX(XXX):XXX-XXX} {WB} {Bovine}
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PSCD1/Cytohesin 1 Rabbit pAb(bs-6707R)-50ul/100ul/200ul
￥1180 - 2800
