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ANGPTL3 Rabbit pAb(bs-5918R)-5

0ul/100ul
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  • ¥1180 - 1980
  • Bioss已认证
  • bs-5918R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    产品编号bs-5918R
    英文名称ANGPTL3 Rabbit pAb
    中文名称血管生成素样蛋白3抗体
    英文别名ANG 5; ANG-5; ANG5; Angiopoietin 5; Angiopoietin like 3; Angiopoietin related protein 3; Angiopoietin-5; Angiopoietin-like protein 3; Angiopoietin-related protein 3; ANGL3_HUMAN; ANGPT5; FHBL2.
    产品应用WB=1:500-2000, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human ANG5/ANGPTL3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量49 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cardiovascular > Angiogenesis > Growth Factors > VEGF > VEGF

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Types of disease > Obesity

    Signal Transduction > Metabolism > Energy Metabolism

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Secreted
    组织特异性Expressed principally in liver. Weakly expressed in kidney.
    相似性Contains 1 fibrinogen C-terminal domain.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {ELISA}{1:5000-10000}

     

    产品细节图片1
    Sample:
    Lane 1: Human HL-60 cell Lysates
    Lane 2: Human HepG2 cell Lysates
    Lane 3: Human 293T cell Lysates
    Lane 4: Human Raji cell Lysates
    Lane 5: Human MOLT4 cell Lysates
    Primary: Anti-ANGPTL3 (bs-5918R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 49kDa
    Observed band size: 60kDa

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    图标文献和实验
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    • Immunochemical Detection of a Fluorophore Derived from the Lipid Peroxidation Product 4-Hydroxy-2-Nonenal and Lysine

      = NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific

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      GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin

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