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产品信息以Bioss网站为准
- 规格:
50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-3922R |
| 英文名称 | ADCY5 Rabbit pAb |
| 中文名称 | 腺苷酸环化酶5抗体 |
| 英文别名 | AC 5; AC5; ADCY 5; Adcy5; ADCY5_HUMAN; Adenylate cyclase type 5; Adenylate cyclase type V; Adenylyl cyclase 5; ATP pyrophosphate lyase 5; ATP pyrophosphate-lyase 5. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ADCY5 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 139 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy Metabolism > Types of disease > Cancer Signal Transduction > Metabolism > Energy Metabolism Signal Transduction > Signaling Pathway > Calcium Signaling |
| 亚基 | Part of a complex containing AKAP5, ADCY6, PDE4C and PKD2. Interacts with RAF1. |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. Cell projection, cilium. |
| 翻译后修饰 | Phosphorylated by RAF1. |
| 相似性 | Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Contains 2 guanylate cyclase domains. |
| 功能 | This is a membrane-bound, calcium-inhibitable adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Pancreas (Mouse) Lysate at 40 ug
Primary: Anti-ADCY5 (bs-3922R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 139 kD
Observed band size: 139 kD
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文献和实验[IF={{ 5.4 }}] {Taotao Li. et al. Rosemary (Rosmarinus officinalis L.) hydrosol based on serotonergic synapse for insomnia. J ETHNOPHARMACOL. 2023 Jul;:116984} {IHC,WB} {Rat}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
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.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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