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APOA4 Rabbit pAb(bs-3876R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-3876R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-3876R
    英文名称APOA4 Rabbit pAb
    中文名称载脂蛋白A4抗体
    英文别名Apo AIV; APOA 4; Apolipoprotein A IV; MGC142154; MGC142156.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Rat (Mouse, Dog, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human APOA4
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量44 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Cellular metabolic process

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of lipids and lipoproteins

    Cardiovascular > Atherosclerosis > Lipid transport

    Cardiovascular > Atherosclerosis > Lipoprotein metabolism

    Cardiovascular > Lipids / Lipoproteins > Lipoproteins/Apolipoproteins > Apolipoproteins

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipid metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Lipoprotein metabolism

    Metabolism > Types of disease > Cancer

    Metabolism > Types of disease > Heart disease

    Signal Transduction > Metabolism > Lipid metabolism

    亚细胞定位Secreted.
    组织特异性Synthesized primarily in the intestine and secreted in plasma.
    翻译后修饰Phosphorylation sites are present in the extracellular medium.
    相似性Belongs to the apolipoprotein A1/A4/E family.
    功能May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料APOA4 (apolipoprotein A-IV) is a component of HDL and chylomicrons. Its primary site of synthesis is the intestine, in association with lymph chylomicron particles. Although its precise function is not known, APOA4 is a potent activator of lecithin-cholesterol acyltransferase (LCAT) in vitro. In rodents, Apo A-IV inhibits gastric emptying and serves as a satiety factor whose synthesis and secretion are increased by the ingestion of dietary fat. It also possesses anti-inflammatory and antiatherogenic properties

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Brain (Rat) Lysate at 30 ug
    Kidney (Rat) Lysate at 30 ug
    Primary: Anti-APOA4 (bs-3876R) at 1/200 dilution
    Secondary: HRP conjugated Goat-Anti-rabbit IgG (bs-0295G-HRP) at 1/3000 dilution
    Predicted band size: 42 kD
    Observed band size: 42 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 5.008 }}] {Wang et al. Proteome-based identification of apolipoprotein A-IV as an early diagnostic biomarker in liver fibrosis. (2017) Oncotarge. 8:88951-88964} {WB} {Rat}

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    文献支持
    APOA4 Rabbit pAb(bs-3876R)-50ul/100ul/200ul
    ¥1180 - 2800