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Creatine kinase B type Rabbit

pAb(bs-11989R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-11989R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-11989R
    英文名称Creatine kinase B type Rabbit pAb
    中文名称脑肌酸激酶BCK抗体
    英文别名B CK; B CK; B-CK; BB-CK; BCK; Brain creatine kinase; Ckb; CKBB; CK-BB; Creatine kinase B; Creatine kinase B chain; Creatine kinase B-type; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine Kinase BB Isoenzyme; Creatine kinase brain; Creatine phosphokinase BB; KCRB_HUMAN.
    中文别名Creatine Kinase MB
    产品应用Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Chicken, Cow, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Creatine kinase B type
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量43 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Integration of energy metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Integration of energy

    Metabolism > Types of disease > Cancer

    Neuroscience > Neurotransmission > Intracellular Signaling > Kinases

    Signal Transduction > Metabolism > Energy Metabolism

    亚基Dimer of identical or non-identical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
    亚细胞定位Cytoplasmic and Mitochondrial
    相似性Belongs to the ATP:guanido phosphotransferase family.
    Contains 1 phosphagen kinase C-terminal domain.
    Contains 1 phosphagen kinase N-terminal domain.
    功能Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain. Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Creatine Kinase MB(CK-MB) isoenzyme is predominantly found in the myocardium (heart muscle). Following a heart attack (myocardial infarction), damaged cells release CK-MB into the blood; these elevated CK levels can be seen 4-8 hours post-infarction and remain elevated for a few days. This makes creatine kinase a useful biomarker for assessing damage to CK-rich tissues, as in cases of rhabdomyolysis (severe muscle breakdown), acute kidney injury, and heart attack.

     

    应用推荐稀释比例
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Blank control: RSC96(blue), the cells were fixed with 2% P‌‌araformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice..
    Isotype Control Antibody: Rabbit IgG(orange) ; Secondary Antibody: Goat anti-rabbit IgG-FITC(white blue), Dilution: 1:100 in 1 X PBS containing 0.5% BSA ; Primary Antibody Dilution: 1μg in 100 μL1X PBS containing 0.5% BSA(green).

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    Creatine kinase B type Rabbit pAb(bs-11989R)-50ul/100ul/200ul
    ¥1180 - 2800