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PCK2 Rabbit pAb(bs-5002R)-50ul

/100ul/200ul

价格￥1180 - 2800

品牌Bioss
货号bs-5002R
更新日期2025年10月16日

应用范围产品信息以Bioss网站为准

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应用范围：
产品信息以Bioss网站为准
规格：
50ul/100ul/200ul

规格：	50ul	产品价格：	￥1180.0
规格：	100ul	产品价格：	￥1980.0
规格：	200ul	产品价格：	￥2800.0

产品编号	bs-5002R
英文名称	PCK2 Rabbit pAb
中文名称	磷酸羧化酶2抗体
英文别名	EC 4.1.1.32; GTP mitochondrial precursor; HGNC:8725; mitochondrial; Mitochondrial phosphoenolpyruvate carboxykinase 2; OTTHUMP00000164700; PCK2; PCKGM_HUMAN; PE; PEP carboxykinase; PEPCK; PEPCK deficiency mitochondrial; PEPCK M; PEPCK-M; PEPCK2; phosphoenolpyruvate carboxykinase [GTP]; phosphoenolpyruvate carboxykinase 2(mitochondrial); phosphoenolpyruvate carboxykinase 2 mitochondrial; phosphoenolpyruvate carboxylase; phosphopyruvate carboxylase.
产品应用	ELISA=1:5000-10000 Not yet tested in other applications. Optimal working dilutions must be determined by the end user.
交叉反应	(Human, Mouse, Rat, Pig, Cow, Horse, Rabbit)
抗体来源	Rabbit
免疫原	KLH conjugated synthetic peptide derived from human PCK2
亚型	IgG
性状	Liquid
纯化方法	affinity purified by Protein A
克隆类型	Polyclonal
理论分子量	67 kDa
浓度	1mg/ml
储存液	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究领域	Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates Cardiovascular > Lipids / Lipoproteins > Lipid Metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Lipid and lipoprotein metabolism > Cholesterol Metabolism Metabolism > Pathways and Processes > Mitochondrial Metabolism > Mitochondrial markers Metabolism > Types of disease > Obesity Signal Transduction > Metabolism > Mitochondrial Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > PKC
亚基	Monomer.
亚细胞定位	Mitochondrion.
翻译后修饰	Phosphorylated upon DNA damage, probably by ATM or ATR.
相似性	Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
功能	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity).
保存条件	Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料	PCK2 is a a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.

应用	推荐稀释比例
{ELISA}	{1:5000-10000}

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文献和实验

该产品被引用文献

[IF={{ 4.533 }}] {Huiying Gu. et al. Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes. Mol Ther-Meth Clin D. 2020 Sep;18:811} {WB} {Mouse}

[IF={{ 3.3 }}] {Yue Pang. et al. Expression Regulation of Gluconeogenesis Related Genes in Ovine Skeletal Muscle Cells. FRONT BIOSCI-LANDMRK. 2024 Jun;29(6):237} {IF} {Sheep}

[IF={{ 2.718 }}] {Naomi Nishio. et al. Hen egg only diets support healthy aging in adult mice. J ANIM PHYSIOL AN N. 2023 Jan;:} {WB} {Mouse}

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