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GOLPH3 Rabbit pAb(bs-13488R)-5

0ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-13488R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-13488R
    英文名称GOLPH3 Rabbit pAb
    中文名称高尔基体磷蛋白3抗体
    英文别名Coat protein GPP34; FLJ90675; Golgi peripheral membrane protein 1, 34 kDa; Golgi phosphoprotein 3(coat protein); Golgi phosphoprotein 3; GOLP3_HUMAN; Golph3; GPP34; MIDAS; Mitochondrial DNA absence factor.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Chicken, Dog, Cow, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human GOLPH3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量34 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Signal Transduction > Protein Trafficking > Golgi Proteins

    Signal Transduction > Protein Trafficking > Vesicle Transport > Coat Proteins

    Tags & Cell Markers > Subcellular Markers > Organelles > Golgi

    亚基Homodimer. Interacts with VPS35.
    亚细胞定位Cell membrane. Endosome. Cytoplasm. Golgi apparatus > Golgi stack membrane. Mitochondrion intermembrane space.
    组织特异性Detected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
    翻译后修饰Phosphorylated.
    相似性Belongs to the GOLPH3/VPS74 family.
    功能Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. GOLPH3L (golgi phosphoprotein 3-like), also known as GPP34R, is a 285 amino acid cytoplasmic protein that localizes to the Golgi apparatus. Belonging to the GOLPH3/VPS74 family, GOLPH3L may have a regulatory role in Golgi trafficking. GOLPH3L is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Hela(Human) Cell Lysate at 30 ug
    Primary: Anti- GOLPH3 (bs-13488R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 34 kD
    Observed band size: 33 kD

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    [IF={{ 4.9 }}] {Jingni Li. et al. Selenium alleviates cadmium-induced Golgi stress via HSPB7/GM130/CX-43 axis in the heart of sheep. J NUTR BIOCHEM. 2025 Jun;:109993} {WB} {Sheep}

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    GOLPH3 Rabbit pAb(bs-13488R)-50ul/100ul/200ul
    ¥1180 - 2800