Sample:
Lane 1: Cerebellum (Mouse) Lysate at 40 ug
Lane 2: Spinal cord (Mouse) Lysate at 40 ug
Lane 3: Stomach (Mouse) Lysate at 40 ug
Lane 4: Cerebellum (Rat) Lysate at 40 ug
Lane 5: Spinal cord (Rat) Lysate at 40 ug
Primary: Anti-5HT3A Receptor (bs-12051R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52-55 kD
Observed band size: 50 kD
- ￥1180 - 2800
- Bioss
- bs-12051R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 应用范围：
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12051R |
| 英文名称 | 5HT3A Receptor Rabbit pAb |
| 中文名称 | 5-羟色胺受体3A抗体 |
| 英文别名 | SR-3A; 5 HT 3; 5 HT3 receptor; 5 HT3A; 5 HT3A receptor; 5 HT3B; 5 HT3R; 5 HT3RA; 5 HTR3B; 5 hydroxytryptamine(serotonin) receptor 3A; 5 Hydroxytryptamine 3 receptor B subunit; 5 Hydroxytryptamine receptor 3; 5 Hydroxytryptamine receptor 3 subunit B; 5 Hydroxytryptamine receptor 3B; 5 Hydroxytryptamine serotonin receptor 3B; 5-HT-3; 5-HT3-A; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT 3; 5HT 3A; 5HT receptor; 5HT3 serotonin receptor; 5HT3A_HUMAN; 5HT3R; HTR 3; HTR3; Htr3a; HTR3B; Serotonin gated ion channel receptor; Serotonin receptor 3; Serotonin receptor 3A; Serotonin receptor 3B; Serotonin-gated ion channel receptor 3a; Serotonin-gated ion channel receptor. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse, Rat (Dog, Pig, Cow, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human 5HT3A Receptor |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 53 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Types of disease > Obesity Neuroscience > Neurotransmission > Receptors / Channels > GPCR > Serotonin Receptors Neuroscience > Neurotransmission > Receptors / Channels > Ligand-Gated Ion Channels > More Channels |
| 亚基 | Forms pentahomomeric complex as well as pentaheteromeric complex with HTR3B or HTR3C or HTR3D or HTR3E; homomeric complex is functional but exhibits low conductance with modified voltage dependence, and decreased agonist and antagonist affinity. Interacts with RIC3. |
| 亚细胞定位 | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
Lane 1: Heart (Mouse) Lysate at 40 ug
Lane 2: Heart (Rat) Lysate at 40 ug
Primary: Anti-5HT3A Receptor (bs-12051R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52-55 kD
Observed band size: 50 kD
Lane 1: Heart (Mouse) Lysate at 40 ug
Lane 2: Heart (Rat) Lysate at 40 ug
Primary: Anti-5HT3A Receptor (bs-12051R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52-55 kD
Observed band size: 50 kD
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5HT3A Receptor Rabbit pAb(bs-12051R)-50ul/100ul/200ul
￥1180 - 2800
