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- bs-5780R
- 2025年10月16日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-5780R |
| 英文名称 | TNFC Rabbit pAb |
| 中文名称 | 肿瘤坏死因子C/淋巴毒素β抗体 |
| 英文别名 | LT beta; LTB; lymphotoxin beta(TNF superfamily, member 3); lymphotoxin beta; lymphotoxin-beta; p33; TNF C; TNFC; TNFSF3; tumor necrosis factor C(lymphotoxin beta); tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3. |
| 产品应用 | WB=1:500-2000, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Dog, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TNFC |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 25 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Necrosis Factors Immunology > Innate Immunity > Cytokines > TNF Superfamily Signal Transduction > Growth Factors/Hormones > TNF |
| 亚基 | Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits. |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein (Potential). |
| 组织特异性 | Spleen and thymus. |
| 相似性 | Belongs to the tumor necrosis factor family. |
| 功能 | Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex and this complex is the primary ligand for the lymphotoxin-beta receptor. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is probably non-functional. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {ELISA} | {1:5000-10000} |
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