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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-7054R |
| 英文名称 | ELOVL5 Rabbit pAb |
| 中文名称 | 长链脂肪酸延长酶长ELOVL5抗体 |
| 英文别名 | 3 keto acyl CoA synthase ELOVL5; 3-keto acyl-CoA synthase Elovl5; dJ483K16.1; Elongation of very long chain fatty acids like 5; Elongation of very long chain fatty acids protein 5; ELOV5_HUMAN; ELOVL 5; ELOVL family member 5; ELOVL family member 5 elongation of long chain fatty acids; ELOVL family member 5, elongation of long chain fatty acids(FEN1/Elo2, SUR4/Elo3-like, yeast); ELOVL fatty acid elongase 5; ELOVL2; elovl5; Fatty acid elongase 1; HELO1; Homolog of yeast long chain polyunsaturated fatty acid elongation enzyme 2; OTTHUMP00000017867; RP3 483K16.1. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Rat (Mouse, Dog, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human ELOVL5 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 33 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Lipids / Lipoproteins > Fatty Acids > Synthesis Metabolism > Pathways and Processes > Redox metabolism > Fatty acid oxidation Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
| 组织特异性 | Ubiquitous. Highly expressed in the adrenal gland and testis. Weakly expressed in prostate, lung and brain. |
| 相似性 | Belongs to the ELO family. |
| 功能 | Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Cerebrum (Rat) Lysate at 40 ug
Primary: Anti- ELOVL5 (bs-7054R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 34 kD

Lane 1: Rat Adrenal gland tissue lysates
Lane 2: Human Molt-4 cell lysates
Lane 3: Human HepG2 cell lysates
Lane 4: Human Jurkat cell lysates
Lane 5: Human U251 cell lysates
Primary: Anti-ELOVL5 (bs-7054R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kDa
Observed band size: 33 kDa
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文献和实验[IF={{ 5.3 }}] {Guanlin Wu. et al. miR-218-5p promotes hepatic lipogenesis through targeting Elovl5 in non-alcoholic fatty liver disease. BIOCHEM PHARMACOL. 2024 Aug;226:116411} {WB} {Mouse}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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