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- bs-5796R
- 2025年10月16日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-5796R |
| 英文名称 | BCL2L10 Rabbit pAb |
| 中文名称 | BCL2样10促凋亡蛋白抗体 |
| 英文别名 | Anti apoptotic protein NrH; Anti-apoptotic protein NrH; Apoptosis regulator Bcl B; Apoptosis regulator Bcl-B; B2L10_HUMAN; BCL B; Bcl-2-like protein 10; Bcl2 L 10; BCL2 like 10(apoptosis facilitator); BCL2 like 10 protein; Bcl2-L-10; Bcl2l10; BCLB; Boo; Diva; MGC129810; MGC129811; Nrh. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | (Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human BCL2L10 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 22 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cell Death > Apoptosis > Apoptosis Markers > Bcl 2 family Cancer > Cell Death > Apoptosis > Metabolism Cancer > Invasion/microenvironment > Apoptosis > Bcl 2 family Cancer > Oncoproteins/suppressors > Oncoproteins > Cell survival & death Cancer > Tumor biomarkers > Oncoproteins Cell Biology > Apoptosis > Intracellular > Bcl2 Family Metabolism > Pathways and Processes > Metabolism processes > Apoptosis |
| 亚基 | Binds to Bcl-2, Bcl-X and BAX. Interacts with APAF1. |
| 亚细胞定位 | Mitochondrion. Nucleus membrane. |
| 组织特异性 | Widely expressed in adult tissues. |
| 相似性 | Belongs to the Bcl-2 family. |
| 功能 | Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1. |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 5.572 }}] {Shaohua Hou. et al. Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors. Eur J Med Chem. 2021 Aug;220:113482} {WB} {Human}
[IF={{ 5.2 }}] {Alaa Wahba. et al.Afobazole alleviates streptozotocin-induced diabetic nephropathy in rats via hypoglycemic, antioxidant, anti-inflammatory, and anti-apoptotic properties: Role of the S1R/Nrf2 antioxidant axis.life sciences.2025 Feb 15:363:123410.} {IHC} {rat}
[IF={{ 1.986 }}] {Huang,et al.Role of BCL2L10 in regulating buffalo (Bubalus bubalis) oocyte maturation.(2018) Theriogenology. 110:1-7.} {IHC,ICC} {Buffalo}
[IF={{ 0.219 }}] {Wang,et al.Yisui shengxue granule, a traditional Chinese medicine compound preparation, can up-regulate the expression of GM-CSF and its receptor in mice bone marrow after irradiation.(2017) Biomedical Research. 28:.} {ICC} {Mouse}
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GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
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