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- 2025年10月16日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-7887R |
| 英文名称 | Cyclin K Rabbit pAb |
| 中文名称 | 周期素K抗体 |
| 英文别名 | CCNK; CCNK_HUMAN; CPR 4; CPR4; Cyclin K; Cyclin-K; CyclinK; MGC9113. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Chicken, Dog, Pig, Cow, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Cyclin K/CCNK |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 64 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cell Biology > Cell Cycle > Cyclins > Other Cyclins Epigenetics and Nuclear Signaling > Cell cycle > Cyclins > Other Cyclins Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚基 | Part of a cyclin-kinase pair in the RNA polymerase IIholoenzyme. Binds to CDK9. |
| 组织特异性 | Ubiquitously expressed. Highest levels intestis. |
| 相似性 | Belongs to the cyclin family. Cyclin C subfamily. |
| 功能 | May play a role in transcriptional regulation. In vitro,is associated with a kinase activity toward both RNA polymerase IIC-terminal domain and CDK2 (CAK). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | May play a role in transcriptional regulation. In vitro, is associated with a kinase activity toward both RNA polymerase II C-terminal domain and CDK2 (CAK).Tissue specificity: Ubiquitously expressed. Highest levels in testis. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验-competitiveinhibitors of GSK-3 are indirubins (19) , paullones (20) , anilinomaleimides(21) , and other small molecules (22) . However,these inhibitors are not GSK-3 specific and they also inhibit cyclin-dependent kinases (CDKs), due to the highly related aminoacid
Studies of the Ubiquitin Proteasome System
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GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
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