P2Y2 Rabbit pAb(bs-4180R)-50ul/100ul/200ul
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P2Y2 Rabbit pAb(bs-4180R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-4180R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-4180R
    英文名称P2Y2 Rabbit pAb
    中文名称嘌呤ATP受体抗体
    英文别名P2Y2R; ATP receptor; HP2U; Human P2U nucleotide receptor mRNA complete cds; P2RU1; P2RY2; P2RY2_HUMAN; P2U nucleotide receptor; P2U purinoceptor 1; P2U1; P2UR; P2Y purinoceptor 2; P2Y2; P2Y2R; Purinergic receptor; Purinergic receptor P2Y G protein coupled 2; Purinergic receptor P2Y2; Purinoceptor P2Y2.
    产品应用WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Dog, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human P2Y2R
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量41 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Spleen, testis, kidney, liver, lung, heart and brain.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料 The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to both adenosine and uridine nucleotides. It may participate in control of the cell cycle of endometrial carcinoma cells. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq].

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}
    {ELISA}{1:5000-10000}

     

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    图标文献和实验
    该产品被引用文献

    [IF={{ 6.1 }}] {Xue-qi Liu. et al. Blocking ATP-P1Rs axis attenuate alcohol-related liver fibrosis. LIFE SCI. 2023 Jun;:121896} {IHC} {Mouse}

    [IF={{ 4.162 }}] {Zhen-Ni Liu. et al. Blockade of the P2Y2 Receptor Attenuates Alcoholic Liver Inflammation by Targeting the EGFR-ERK1/2 Signaling Pathway. DRUG DES DEV THER. Drug Des Dev Ther. 2022 Apr;16:1107-1120} {IHC} {Mouse}

    [IF={{ 3.361 }}] {Liu ZN et al. Regulation of CD39 expression in ATP-P2Y2R-mediated alcoholic liver steatosis and inflammation. Int Immunopharmacol. 2019 Oct 19;77:105915.} {WB} {Mouse}

    [IF={{ 2.9 }}] {Mengjie Chen. et al. Long noncoding RNA MALAT1 as a ceRNA drives mouse fibroblast activation via the miR-335-3p/P2ry2 axis. PLOS ONE. 2024 Aug;19(8):e0308723} {WB} {Mouse}

    [IF={{ 1.42 }}] {Liu, Yuan-Mei, et al. "Expression of the P2Y2 receptor in the terminal rectum of fetal rats with anorectal malformation." International Journal of Clinical and Experimental Medicine 8.2 (2015): 1669-1676.} {IHC} {="Rat"}

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    文献支持
    P2Y2 Rabbit pAb(bs-4180R)-50ul/100ul/200ul
    ¥1180 - 2800