Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti- KCC4 (bs-12170R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 119 kD
Observed band size: 119 kD
- ￥1180 - 2800
- Bioss
- bs-12170R
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
phospho-ATG1 (Ser556) Rabbit pAb, RBITC conjugated(bs-3464R-RBITC)-100ul
￥2980
LMTK3 Rabbit pAb(bs-18317R)-50ul/100ul/200ul
￥1180
HSPB6 Recombinant Mouse mAb(bsm-60365M)-50ul/100ul/25ul
￥800
GTPase HRAS Rabbit pAb, HRP conjugated(bs-6165R-HRP)-100ul
￥2980heatstable enterotoxin 1 Rabbit pAb(bs-8858R)-50ul/100ul/200ul
￥1180
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-12170R |
| 英文名称 | KCC4 Rabbit pAb |
| 中文名称 | 钾氯离子转运蛋白KCC4抗体 |
| 英文别名 | D13Ertd261e; Electroneutral potassium-chloride cotransporter 4; Furosemide sensitive KCl cotransporter 4; K Cl cotransporter KCC4; K-Cl cotransporter 4; Potassium/chloride transporter KCC4; S12A7_HUMAN; SLC12A7; Solute carrier family 12(potassium/chloride transporters), member 7; Solute carrier family 12 member 7; Solute carrier family 12, member 7. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Pig, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human KCC4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 119 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > More Ion Channels Neuroscience > Neurotransmission > Receptors / Channels > Potassium Channels Neuroscience > Sensory System > Auditory system |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Detected in muscle, brain, lung, heart and kidney. |
| 相似性 | Belongs to the SLC12A transporter family. |
| 功能 | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
KCC4 Rabbit pAb(bs-12170R)-50ul/100ul/200ul
￥1180 - 2800
