BPY2 Rabbit pAb(bs-12882R)-50ul/100ul/200ul

BPY2 Rabbit pAb(bs-12882R)-50u

l/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-12882R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-12882R
    英文名称BPY2 Rabbit pAb
    中文名称睾丸特异性碱性蛋白Y2抗体
    英文别名Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human BPY2
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量12 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚基Interacts with MAP1S. Interacts with UBE3A (via HECTdomain).
    组织特异性Expressed exclusively in testis. Expressed in ejaculated spermatozoa of germ cell. Expressed in the nuclei of spermatogonia, spermatocytes, and round spermatids, except elongated spermatids (at protein level).
    相似性Belongs to the VCX/VCY family.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Mammalian spermatogenesis is a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    BPY2 Rabbit pAb(bs-12882R)-50u
    Sample: HL-60 Cell (Human) Lysate at 40 ug
    Primary: Anti-BPY2 (bs-12882R) at 1/300 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 12 kD
    Observed band size: 12 kD

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