Sample:
Lane 1: Human HepG2 cell lysates
Lane 2: Human HeLa cell lysates
Primary: Anti-CCBR1 (bs-6883R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 57 kDa
- ￥1180 - 1980
- Bioss
- bs-6883R
- 2026年05月21日
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- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 产品编号 | bs-6883R |
| 英文名称 | CCBR1 Rabbit pAb |
| 中文名称 | 钙离子通道阻端耐药蛋白CCBR1抗体 |
| 英文别名 | Amino acid transport system xc xCT antibody; Amino acid transport system xc-antibody Calcium channel blocker resistance protein CCBR1; Calcium channel blocker resistance protein CCBR1 antibody; CCBR1; Cysteine/glutamate transporter antibody; cystine/glutamate transporter; SLC7A11; Solute carrier family 7(anionic amino acid transporter light chain, xc-system), member 11; solute carrier family 7; Solute carrier family 7 member 11; Solute carrier family 7, (cationic amino acid transporter, y+system) member 11; xCT; XCT_HUMAN. |
| 产品应用 | WB=1:500-1000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human xCT/CCBR1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 55 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 亚基 | Disulfide-linked heterodimer with the amino acid transport protein SLC3A2/4F2hc (By similarity). |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 相似性 | Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family. |
| 功能 | Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-1000} |
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CCBR1 Rabbit pAb(bs-6883R)-50ul/100ul
￥1180 - 1980
