TMEM123 | Porimin Rabbit pAb(bs-7674R)-50ul/100ul/200ul产品图
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TMEM123 | Porimin Rabbit pAb(b

s-7674R)-50ul/100ul/200ul
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  • ¥1180 - 2800
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  • bs-7674R
  • 2026年10月13日
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-7674R
    英文名称Porimin Rabbit pAb
    中文名称前细胞胀亡受体诱导膜损伤蛋白抗体
    英文别名KCT3; Keratinocytes associated transmembrane protein 3; Pro oncosis receptor inducing membrane injury; Serine/threonine rich receptor; TMEM123; Transmembrane protein 123; PORIM_HUMAN.
    产品应用WB=1:500-2000, Flow-Cyt=2ug/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human, Mouse (Rat, Dog, Pig, Cow, Horse)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Porimin
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量19 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    亚细胞定位Membrane; Single-pass type I membrane protein.
    组织特异性Ubiquitous. Not expressed in ovary. Expressed in keratinocytes.
    相似性Belongs to the CD164 family.
    功能Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {Flow-Cyt}{2ug/Test}

     

    产品细节图片1
    Sample:
    _x000D_ Skin (Mouse) Lysate at 40 ug
    _x000D_ Skin (Rat) Lysate at 40 ug
    _x000D_ Primary: Anti- Porimin (bs-7674R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 19 kD
    _x000D_ Observed band size: 64 kD
    _x000D_
    产品细节图片2
    Blank control:Molt4.
    _x000D_ Primary Antibody (green line): Rabbit Anti-Porimin antibody (bs-7674R)
    _x000D_ Dilution: 2μg /10^6 cells;
    _x000D_ Isotype Control Antibody (orange line): Rabbit IgG .
    _x000D_ Secondary Antibody : Goat anti-rabbit IgG-PE
    _x000D_ Dilution: 1μg /test.
    _x000D_ Protocol
    _x000D_ The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed._x000D_
    产品细节图片3
    Sample:
    _x000D_ Embryo (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti- Porimin (bs-7674R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 19 kD
    _x000D_ Observed band size: 74 kD
    _x000D_
    产品细节图片4
    Sample:
    _x000D_ Lymph node (Mouse) Lysate at 40 ug
    _x000D_ Primary: Anti- Porimin (bs-7674R) at 1/1000 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 19 kD
    _x000D_ Observed band size: 74 kD
    _x000D_

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    TMEM123 | Porimin Rabbit pAb(bs-7674R)-50ul/100ul/200ul
    ¥1180 - 2800