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50ul/100ul/200ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 规格: | 200ul | 产品价格: | ¥2800.0 |
| 产品编号 | bs-4974R |
| 英文名称 | Glucose 6 Phosphate Dehydrogenase Rabbit pAb |
| 中文名称 | 葡萄糖-6磷酸脱氢酶抗体 |
| 英文别名 | G6PD; G6PD_HUMAN; G6PD1; G6pdx; Glucose 6 phosphate 1 dehydrogenase; Glucose-6-phosphate 1-dehydrogenase; MET19; POS10; Zwf1p. |
| 中文别名 | 6磷酸葡萄糖脱氢酶; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Glucose 6 Phosphate Dehydrogenase |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 57 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates Cardiovascular > Atherosclerosis > Diabetes associated Cardiovascular > Heart > Cardiac metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Homodimer or homotetramer. |
| 组织特异性 | Isoform Long is found in lymphoblasts, granulocytes and sperm. |
| 相似性 | Belongs to the glucose-6-phosphate dehydrogenase family. |
| 功能 | Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) . Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lymph node (Mouse) Lysate at 40 ug
Primary: Anti- Glucose 6 Phosphate Dehydrogenase (bs-4974R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kD
Observed band size: 57 kD
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文献和实验[IF={{ 4.4 }}] {Defne Engur. et al. Supplemental oxygen alters the pentose phosphate pathway in the developing mouse brain through SIRT signaling. NEUROCHEM INT. 2024 Nov;180:105886} {IHC,WB} {Mouse}
Transplantation Models to Characterize the Mechanisms of Stem Cell–Induced Islet Regeneration
our current knowledge regarding the isolation human bone marrow?derived progenitor cells for the paracrine stimulation of islet regeneration after transplantation into immunodeficient mouse models of diabetes. By using high aldehyde dehydrogenase (ALDHhi
rabbit serum albumin 兔血清白蛋白 R-Sc Reed-Sternberg's cell 瑞-司氏细胞 Z/R Reinheit Zahl 光密度比值 SAV small agranular vesicle 无颗粒小泡 SBA soybean agglutinin 大豆凝集素 SC secretory component 分泌成份 SCV small clear vesicle 清亮小泡 SDS sodium
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