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Glucose 6 Phosphate Dehydrogen

ase Rabbit pAb(bs-4974R)-50ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-4974R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-4974R
    英文名称Glucose 6 Phosphate Dehydrogenase Rabbit pAb
    中文名称葡萄糖-6磷酸脱氢酶抗体
    英文别名G6PD; G6PD_HUMAN; G6PD1; G6pdx; Glucose 6 phosphate 1 dehydrogenase; Glucose-6-phosphate 1-dehydrogenase; MET19; POS10; Zwf1p.
    中文别名6磷酸葡萄糖脱氢酶;
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Mouse (Human, Rat, Cow, Horse, Rabbit, Sheep)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human Glucose 6 Phosphate Dehydrogenase
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量57 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Cancer Metabolism > Metabolic signaling pathway > Metabolism of carbohydrates

    Cardiovascular > Atherosclerosis > Diabetes associated

    Cardiovascular > Heart > Cardiac metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Carbohydrate metabolism

    Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism

    Metabolism > Types of disease > Diabetes

    Metabolism > Types of disease > Heart disease

    Signal Transduction > Metabolism > Energy Metabolism

    亚基Homodimer or homotetramer.
    组织特异性Isoform Long is found in lymphoblasts, granulocytes and sperm.
    相似性Belongs to the glucose-6-phosphate dehydrogenase family.
    功能Produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Defects in G6PD are the cause of chronic non-spherocytic hemolytic anemia (CNSHA) . Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample:
    Lymph node (Mouse) Lysate at 40 ug
    Primary: Anti- Glucose 6 Phosphate Dehydrogenase (bs-4974R) at 1/1000 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 57 kD
    Observed band size: 57 kD

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    图标文献和实验
    该产品被引用文献

    [IF={{ 4.4 }}] {Defne Engur. et al. Supplemental oxygen alters the pentose phosphate pathway in the developing mouse brain through SIRT signaling. NEUROCHEM INT. 2024 Nov;180:105886} {IHC,WB} {Mouse}

    相关实验
    • Transplantation Models to Characterize the Mechanisms of Stem Cell–Induced Islet Regeneration

      our current knowledge regarding the isolation human bone marrow?derived progenitor cells for the paracrine stimulation of islet regeneration after transplantation into immunodeficient mouse models of diabetes. By using high aldehyde dehydrogenase (ALDHhi

    • (共享)免疫单词缩写及翻译

      rabbit serum albumin 兔血清白蛋白 R-Sc Reed-Sternberg's cell 瑞-司氏细胞 Z/R Reinheit Zahl 光密度比值 SAV small agranular vesicle 无颗粒小泡 SBA soybean agglutinin 大豆凝集素 SC secretory component 分泌成份 SCV small clear vesicle 清亮小泡 SDS sodium

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    文献支持
    Glucose 6 Phosphate Dehydrogenase Rabbit pAb(bs-4974R)-50ul/100ul/200ul
    ¥1180 - 2800