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- 2025年10月24日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-3892R |
| 英文名称 | cGMP Rabbit pAb |
| 中文名称 | 环磷酸鸟苷抗体 |
| 英文别名 | Cyclic GMP; Cyclic guanosine monophosphate; Guanosine 3 5 Cyclic Monophosphate. |
| 产品应用 | IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Species independent |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated cGMP |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 0.34521 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Phosphorylation > Ser / Thr Kinases > Other Kinases Signal Transduction > Second Messenger > Nucleotide Messenger > cGMP |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cyclic guanosine monophosphate (cGMP) serves as a second messenger in a manner similar to that observed with cAMP. Peptide hormones, such as the natriuretic factors, activate receptors that are associated with membrane-bound guanylate cyclase (GC). Receptor activation of GC leads to the conversion of GTP to cGMP. Nitric oxide (NO) also stimulates cGMP production by activating soluble GC, perhaps by binding to the heme moiety of the enzyme. Similar to cAMP, cGMP mediates most of its intracellular effects through the activation of specific cGMP dependent protein kinases (PKG). |
| 应用 | 推荐稀释比例 |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 9.685 }}] {Son, Youlim. et al. Mdm1 ablation results in retinal degeneration by specific intraflagellar transport defects of photoreceptor cells. CELL DEATH DIS. 2022 Sep;13(9):1-12} {IF} {Mouse}
[IF={{ 6.1 }}] {Zhi-Yong An. et al. Chenodeoxycholic acid improves oocyte maturation and embryo quality during bisphenol A exposure by activating the EGFR-ERK1/2 signaling pathway. ECOTOX ENVIRON SAFE. 2025 Sep;302:118725} {IF} {Pig}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
48T/96T 2000/3000 进口分装 F19031 兔子脑钠素 / 脑钠尿肽 (rabbit BNP) ELISA 48T/96T 2000/3000 进口分装 F19051 兔环磷酸鸟苷 (rabbit cGMP) ELISA
Theoretical Aspects of the Quantitative Characterization of Ligand Binding
dependences of the binding function ( r ) upon free ligand concentration ( C S ) for various types of acceptor‐ligand interaction. Rectangular hyperbolic dependence (—) for an acceptor with two equivalent and independent sites ( K AS = K 1 = K 2 = K 3 = K
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