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50ul/100ul
| 规格: | 50ul | 产品价格: | ¥1180.0 |
|---|---|---|---|
| 规格: | 100ul | 产品价格: | ¥1980.0 |
| 产品编号 | bs-2619R |
| 英文名称 | IL-20R alpha Rabbit pAb |
| 中文名称 | 白介素20受体α链抗体 |
| 英文别名 | IL-20Rα; Interleukin-20 receptor alpha chain precursor; IL-20RA; IL20 RA; IL-20 RA; E230031K19; FLJ40993; IL-20R1; IL20RA; ZCYTOR7; Interleukin-20 receptor subunit alpha; IL-20 receptor subunit alpha; IL-20R-alpha; IL-20RA; Cytokine receptor family 2 member 8; CRF2-8; Cytokine receptor class-II member 8; I20RA_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human IL-20RA |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 59 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Cell Type Markers > CD > Cytokines Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Heterodimer with IL20RB and heterodimer with IL10RB. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Widely expressed with highest levels in skin and testis and high levels in brain. Highly expressed in psoriatic skin. |
| 相似性 | Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. |
| 功能 | The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is a receptor for interleukin 20 (IL20), a cytokine that may be involved in epidermal function. The receptor of IL20 is a heterodimeric receptor complex consisting of this protein and interleukin 20 receptor beta (IL20B). This gene and IL20B are highly expressed in skin. The expression of both genes is found to be upregulated in Psoriasis. [provided by RefSeq] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |

Lane 1: Mouse Skin tissue lysates
Lane 2: Mouse Kidney tissue lysates
Lane 3: Mouse Testis tissue lysates
Primary: Anti-IL-20R alpha (bs-2619R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 59 kDa
Observed band size: 59 kDa
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文献和实验[IF={{ 6.183 }}] {Madouri F et al. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae.(2018) EBioMedicine. Oct 22.} {IHC} {Mouse}
[IF={{ 5.076 }}] {Liu Shengpeng. et al. IL-20R Activation via rIL-19 Enhances Hematoma Resolution through the IL-20R1/ERK/Nrf2 Pathway in an Experimental GMH Rat Pup Model. Oxid Med Cell Longev. 2021;2021:5913424} {WB,IF} {Rat}
[IF={{ 3.8 }}] {Yuting Jiang. et al. Effects of Interleukin-19 overexpression in the medial prefrontal cortex on anxiety-related behaviors, BDNF expression and p38/JNK/ERK pathways. BRAIN RES BULL. 2024 Jun;212:110952} {WB,IF} {Mouse}
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
Generation of Spatio‐Temporally Controlled Targeted Somatic Mutations in the Mouse
Syringe (1‐ml equipped with a 25‐G needle; Terumo, cat. no. BS‐01 H2516) Gas anesthesia station for rodents (TEM)
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