P2Y10 Rabbit pAb(bs-12070R)-50ul/100ul/200ul产品图

P2Y10 Rabbit pAb(bs-12070R)-50

ul/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-12070R
  • 2025年10月16日
  • 产品信息以Bioss网站为准
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    • 规格:

      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-12070R
    英文名称P2Y10 Rabbit pAb
    中文名称G蛋白偶联嘌呤受体p2y10抗体
    英文别名G protein coupled purinergic receptor P2Y10; P2ry10; P2Y like receptor; P2Y purinoceptor 10; P2Y-like receptor; P2Y10; P2Y10_HUMAN; Purinergic receptor P2Y G protein coupled 10; Putative P2Y purinoceptor 10.
    产品应用WB=1:500-2000, Flow-Cyt=1μg/Test

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat, Horse, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human P2Y10
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量39 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR

    Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR

    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Weakly expressed in blood leukocytes.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Putative receptor for purines coupled to G-proteins.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Nucleotides are important extracellular signaling molecules that mediate several events, such as cell proliferation, differentiation, chemotaxis and cytokine release. The P2 receptor family is activated by the binding of nucleotides and is divided into two subfamilies, designated P2X and P2Y. The P2Y receptor family are G protein-coupled receptors that mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C (PLC). To some extent, the P2Y receptors can also activate potassium channels or, alternatively, inhibit adenylate cyclase and N-type calcium channels in response to extracellular nucleotides. P2Y10 (purinergic receptor P2Y, G-protein coupled, 10), also known as P2RY10, is a 339 amino acid multi-pass membrane protein that is thought to act as a receptor for purines coupled to G-proteins. P2Y10 is found at low levels in blood leukocytes and is upregulated during promyelocytic cell differentiation.

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {Flow-Cyt}{1μg/Test}

     

    产品细节图片1
    Sample:
    HepG2 cell(human) Lysate at 30 ug
    Primary: Anti-P2Y10(bs-12070R) at 1/500 dilution
    Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    Predicted band size: 39kD
    Observed band size: 49 kD
    产品细节图片2
    Blank control (blue line): raji(fixed with pre-warmed 4% P‌‌araformaldehyde for 30min at 37℃)
    Primary Antibody (green line): Rabbit Anti-P2Y10 antibody (bs-12070R),Dilution: 0.2μg /10^6 cells;
    Isotype Control Antibody (orange line): Rabbit IgG .
    Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE,Dilution: 1μg /test.

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