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- 2025年10月16日
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-3662R |
| 英文名称 | WNT10B Rabbit pAb |
| 中文名称 | 信号通路WNT10B抗体 |
| 英文别名 | WN10B_HUMAN; SHFM6; wingless type MMTV integration site family, member 10B; wnt12; WNT10-B. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500, ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human WNT10B |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 40 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Metabolism > Types of disease > Cancer Neuroscience > Neurology process > Metabolism Stem Cells > Signaling Pathways > Wnt > Secreted |
| 亚细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织特异性 | Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain. |
| 相似性 | Belongs to the Wnt family. |
| 功能 | Secreted, extracellular space, extracellular matrix. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region. [provided by RefSeq, Jul 2008] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
| {ELISA} | {1:5000-10000} |
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文献和实验[IF={{ 6.6 }}] {Subin Jeong. et al. Optimization of hair follicle spheroids for the hair-on-a-chip. BIOMATER SCI-UK. 2024 Feb;:} {IF} {Human}
[IF={{ 5.5 }}] {Zhang et al. Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling. (2016) Cell.Physiol.Biochem. 39:360-70} {IHC} {Human}
[IF={{ 4.65 }}] {Zhang, H., et al. "Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling."Cellular Physiology and Biochemistry 39.1 (2016): 360-370.} {WB} {="Human"}
[IF={{ 4.3 }}] {Guanqi Liu. et al.Gingival fibroblasts suppress the osteogenesis process mediated by bone substitute materials via WNT/β-catenin signaling pathway in vitro and in vivo.frontiers in bioengineering and biotechnology.2025 Feb 10:13:1521134.} {IF} {Rat}
[IF={{ 3.553 }}] {Li M et al. Plant MIR156 Regulates Intestinal Growth in Mammals by Targeting the Wnt/β-catenin Pathway. Am J Physiol Cell Physiol. 2019 Jun 5.} {IF,ICC} {Mouse&Pig}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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