CSF3R | G-CSFR/CD114 Rabbit pAb(bs-2574R)-50ul/100ul/200ul产品图
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CSF3R | G-CSFR/CD114 Rabbit pA

b(bs-2574R)-50ul/100ul/200ul
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  • 2026年10月13日
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    北京博奥森生物技术有限公司
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-2574R
    英文名称GCSF Receptor Rabbit pAb
    中文名称粒细胞-巨噬细胞集落刺激因子3受体抗体
    英文别名GCSF Receptor; CD 114; CD114; CD114 antigen; Colony stimulating factor 3 receptor(granulocyte); Colony stimulating factor 3 receptor; CSF 3R; CSF3R; CSF3R_HUMAN; Csfgr; G CSF R; G-CSF receptor; G-CSF-R; G-CSFR; GCSFR; Granulocyte colony stimulating factor receptor; Granulocyte colony stimulating factor receptor precursor; Granulocyte colony-stimulating factor receptor.
    产品应用WB=1:500-2000

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human G-CSFR
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量95 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Oncoproteins/suppressors > Oncoproteins > Growth factor receptors

    Immunology > Innate Immunity > Cytokines > CSFs

    Stem Cells > Hematopoietic Progenitors > Surface Molecules

    亚基Homodimer. The dimeric receptor binds two CSF3 molecules.
    亚细胞定位Isoform 2: Secreted (Probable). Cell membrane; Single-pass type I membrane protein.
    组织特异性One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U937 cells. Isoform GSCFR-3 is highly expressed in placenta.
    相似性Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 5 fibronectin type-III domains.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    功能Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

     

    应用推荐稀释比例
    {WB}{1:500-2000}

     

    产品细节图片1
    Sample: 293T Cell (Human) Lysate at 30 ug
    _x000D_ Primary: Anti- GCSF Receptor (bs-2574R)at 1/300 dilution
    _x000D_ Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
    _x000D_ Predicted band size: 95kD
    _x000D_ Observed band size: 120kD
    _x000D_

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    CSF3R | G-CSFR/CD114 Rabbit pAb(bs-2574R)-50ul/100ul/200ul
    ￥1180 - 2800