Sample: 293T Cell (Human) Lysate at 30 ug
Primary: Anti- GCSF Receptor (bs-2574R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 95kD
Observed band size: 120kD
- ￥1180 - 2800
- Bioss
- bs-2574R
- 2025年10月16日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2574R |
| 英文名称 | GCSF Receptor Rabbit pAb |
| 中文名称 | 粒细胞-巨噬细胞集落刺激因子3受体抗体 |
| 英文别名 | GCSF Receptor; CD 114; CD114; CD114 antigen; Colony stimulating factor 3 receptor(granulocyte); Colony stimulating factor 3 receptor; CSF 3R; CSF3R; CSF3R_HUMAN; Csfgr; G CSF R; G-CSF receptor; G-CSF-R; G-CSFR; GCSFR; Granulocyte colony stimulating factor receptor; Granulocyte colony stimulating factor receptor precursor; Granulocyte colony-stimulating factor receptor. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human G-CSFR |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 95 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Growth factor receptors Immunology > Innate Immunity > Cytokines > CSFs Stem Cells > Hematopoietic Progenitors > Surface Molecules |
| 亚基 | Homodimer. The dimeric receptor binds two CSF3 molecules. |
| 亚细胞定位 | Isoform 2: Secreted (Probable). Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | One or several isoforms have been found in myelogenous leukemia cell line KG-1, leukemia U937 cell line, in bone marrow cells, placenta, and peripheral blood granulocytes. Isoform GCSFR-2 is found only in leukemia U937 cells. Isoform GSCFR-3 is highly expressed in placenta. |
| 相似性 | Belongs to the type I cytokine receptor family. Type 2 subfamily. Contains 5 fibronectin type-III domains. Contains 1 Ig-like C2-type (immunoglobulin-like) domain. |
| 功能 | Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differientation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by the GCSF Receptor gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, of which three are membrane-bound and the one secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 7.5 }}] {Jianhe Huang. et al. Granulocyte colony stimulating factor promotes scarless tissue regeneration. CELL REP. 2024 Oct;43:} {IHC} {Mouse}
[IF={{ 4.671 }}] {Hong L et al. Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. J Mol Cell Biol. 2019 Nov 19. pii: mjz105.} {WB} {Mouse}
[IF={{ 4 }}] {Hong L et al. Protective effects of Human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. J Mol Cell Biol. 2020 Jun 11;12(5):372-385.} {WB} {Human}
[IF={{ 3.777 }}] {Jia-hui Che. et al. Macrophage Polarization in Placenta Accreta and Macrophage-trophoblast Interactions. AM J REPROD IMMUNOL. 2022 Aug;:} {IHC} {Human}
[IF={{ 3.2 }}] {Yoko Fujimaki. et al. Granulocyte colony-stimulating factor promotes regeneration of severed facial nerve in rats. FRONT NEUROSCI-SWITZ. 2024 Dec;18:} {IF} {Rat}
相关实验
, Algermissen, B. et al. 3. Purification of rabbit liver aldehyde oxidase by affinity chromatography on benzamidine Sepharose 6B. J. Chromatogr. (1989), 475 363-72, Stell, J. G. P. et al. 4. The Crystal Structure of a T Cell Receptor in Complex
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GCSF Receptor Rabbit pAb(bs-2574R)-50ul/100ul/200ul
￥1180 - 2800
