Sample:A431 (Human)Cell Lysate at 40 ug
Primary: Anti-TMPRSS4(bs-6286R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 55kD
- ￥1180 - 2800
- Bioss
- bs-6286R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-6286R |
| 英文名称 | TMPRSS4 Rabbit pAb |
| 中文名称 | 膜型丝氨酸蛋白酶2抗体 |
| 英文别名 | MT SP2; Membrane type serine protease 2; TMPRSS 4; TMPRSS3; Transmembrane protease, serine 4; Transmembrane serine protease 3; UNQ776/PRO1570; TMPS4_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Horse) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TMPRSS4 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 48 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Tumor biomarkers > Enzymes Cardiovascular > Atherosclerosis > Diabetes associated Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > TMPRSS Neuroscience > Neurology process > Neurodegenerative disease |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein (Potential). |
| 组织特异性 | High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract. |
| 相似性 | Belongs to the peptidase S1 family.
Contains 1 LDL-receptor class A domain. Contains 1 peptidase S1 domain. Contains 1 SRCR domain. |
| 功能 | Probable protease. Seems to be capable of activating ENaC. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TMPRSS4 is a member of the peptidase S1 family and contains 1 LDL receptor class A domain, 1 peptidase S1 domain and 1 SRCR domain. It is a probable membrane protease capable of activating ENaC and may process sodium channels in endothelial cells. TMPRSS4 is overexpressed in thyroid neoplasms, and splice variants in TMPRSS4 are thought to be linked with different cancers. Three named isoforms are produced by alternative splicing. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:Epithelium (Mouse)Lysate at 40 ug
Primary: Anti-TMPRSS4(bs-6286R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 60kD
Primary: Anti-TMPRSS4(bs-6286R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 60kD
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文献和实验该产品被引用文献
[IF={{ 0 }}] {Wei Wang. et al. Unveiling the impact of C15orf48 on non-small cell lung cancer through NF-kappa B signaling. Biomolecules and Biomedicine. 2024 Nov;:} {WB} {Human}
[IF={{ 0 }}] {Wei Wang. et al.Unveiling the impact of C15orf48 on non-small cell lung cancer through NF-kappa B signaling.BIOMOLECULES AND BIOMEDICINE.2024 Nov 22.} {Western blot} {Human}
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TMPRSS4 Rabbit pAb(bs-6286R)-50ul/100ul/200ul
￥1180 - 2800
