Sample:
Lane 1: Mouse Uterus tissue lysates
Lane 2: Mouse Liver tissue lysates
Lane 3: Rat Uterus tissue lysates
Primary: Anti-AT2R2 (bs-2133R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 50 kDa
- ￥1180 - 2800
- Bioss
- bs-2133R
- 2025年10月24日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Aldolase A Rabbit pAb, BF350 conjugated(bs-2406R-BF350)-100ul
￥2980
SSTR4 Rabbit pAb(bs-21861R)-50ul/100ul/200ul
￥1180
Anti-human CLDN18.2 (Zolbetuximab MMAE Biosimilar)(BIO0951SM)-1mg/5mg/20mg
￥3200
Nrf2 Rabbit pAb, APC conjugated(bs-1074R-APC)-100ul
￥2980NALP5 Rabbit pAb, Biotin conjugated(bs-19006R-Bio)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2133R |
| 英文名称 | AT2R2 Rabbit pAb |
| 中文名称 | 血管紧张素Ⅱ受体2抗体 |
| 英文别名 | AGTR 2; AGTR2; AGTR-2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II Type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; AT2R2 ATGR 2; ATGR2; ATGR-2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Dog, Pig, Horse, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human angiotensin II receptor type 2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 41 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cardiovascular > Atherosclerosis > Apoptosis Cardiovascular > Blood > Blood Pressure regulation Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR Signal Transduction > Signaling Pathway > Lipid Signaling > PLC |
| 亚基 | Interacts with MTUS1. |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Angiotensin II (Ang II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able to function as a substrate for Src kinases and has several putative phosphorylation sites. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
[IF={{ 15.1 }}] {Xin Zhang. et al. Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single-Cell Transcriptomics. Advanced Science. 2023 Nov;:2303753} {IF} {Human}
相关实验
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
技术资料暂无技术资料 索取技术资料
文献支持
AT2R2 Rabbit pAb(bs-2133R)-50ul/100ul/200ul
￥1180 - 2800
