Sample:
Lane 1: Mouse Kidney tissue lysates
Lane 2: Mouse Heart tissue lysates
Primary: Anti-CALCRL (bs-1860R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
- ￥1180 - 2800
- Bioss
- bs-1860R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1860R |
| 英文名称 | CALCRL Rabbit pAb |
| 中文名称 | 降钙素基因相关肽1型受体抗体 |
| 英文别名 | CGRPR; CRLR; calcitonin receptor like precursor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; CGRP type 1 receptor; Calcitonin gene related peptide type 1 receptor; Calcitonin receptor like; Calcitonin Receptor Like Receptor; CGRP type 1 receptor; CALRL_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse (Human, Rat) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CGRPR1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 50 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Signaling Pathway > Calcium Signaling Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚基 | Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3. |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Predominantly expressed in the lung and heart. |
| 相似性 | Belongs to the G-protein coupled receptor 2 family. |
| 功能 | Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | bs-1860P is one synthetic peptide derived from human CGRPR1.CRLR is a receptor for calcitonin gene related peptide type 1. The activity of CRLR is mediated by G proteins which activate adenylyl cyclase. CRLR expression has been reported in brain, lung, blood vessel, liver, and intestinal tract. ESTs have been isolated from B Cell/lung/testis, bone marrow, embryo, lung, and synovium libraries. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
Lane 1: Rat Lung tissue lysates
Primary: Anti-CALCRL (bs-1860R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kDa
Observed band size: 53 kDa
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文献和实验该产品被引用文献
[IF={{ 6.6 }}] {Romina Mancinelli. et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. CELLS-BASEL. 2022 Jan;11(9):1591} {IHC} {Mouse}
[IF={{ 6.116 }}] {E.R. Moore. et al. CGRP and Shh Mediate the Dental Pulp Cell Response to Neuron Stimulation:. J DENT RES. 0;():} {IHC} {Mouse}
[IF={{ 5.9 }}] {Shusuke Iwata. et al. Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway. NUTRIENTS. 2023 Jan;15(13):2941} {IHC} {Mouse}
[IF={{ 5.9 }}] {Jiang Shan. et al. Transcript-dependent effects of the CALCA gene on the progression of post-traumatic osteoarthritis in mice. COMMUN BIOL. 2024 Feb;7(1):1-12} {IF} {Mouse}
[IF={{ 5.736 }}] {Jessika Appelt. et al. The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing. Ebiomedicine. 2020 Sep;59:102970} {IF,IHC} {Mouse}
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CALCRL Rabbit pAb(bs-1860R)-50ul/100ul/200ul
￥1180 - 2800
