Sample:
Lane 1: Rat Embryo tissue lysates
Lane 2: Rat Uterus tissue lysates
Primary: Anti-Midkine (bs-1849R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 13.4 kDa
Observed band size: 16 kDa
- ￥1180 - 2800
- Bioss
- bs-1849R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-1849R |
| 英文名称 | Midkine Rabbit pAb |
| 中文名称 | 中期因子/肝素结合生长因子抗体 |
| 英文别名 | Amphiregulin associated protein; ARAP; FLJ27379; MDK; Midgestation and kidney protein; MK 1; MK; MK1; NEGF 2; NEGF2; neurite growth promoting factor 2; Neurite outgrowth promoting protein; MK_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Rat (Mouse, Dog, Cow, Horse, Fruit Fly) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human Midkine |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 13.4 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Neuroscience > Neurology process > Growth and Development > Neurotrophins Neuroscience > Neurology process > Neurogenesis |
| 亚基 | Homodimer. Interacts with ALK. |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the pleiotrophin family. |
| 功能 | Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development (By similarity). |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Midkine exhibits neurite outgrowth-promoting activity and may play a role in nervous system development and/or maintenance. Its expression is predominant only for a short period from approximately one-half to two-thirds of the way through gestation; before and after that, it is barely detectable. Midkine was first found in differentiating mouse teratocarcinoma cells. It has neurotrophic activities and is mitogenic to certain, but not to all, fibroblast cell lines. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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Midkine Rabbit pAb(bs-1849R)-50ul/100ul/200ul
￥1180 - 2800
