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- bs-2420R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-2420R |
| 英文名称 | NCR2 Rabbit pAb |
| 中文名称 | 细胞毒性受体NK-p44抗体 |
| 英文别名 | Natural killer cell p44-related protein; CD336; CD336 antigen; LY95; Lymphocyte antigen 95 homolog; Lymphocyte antigen 95(activating NK receptor; NK p44); Natural cytotoxicity triggering receptor 2; Natural killer cell p44-related protein; NK cell activating receptor; NK p44; NKp44; NCTR2_HUMAN; dJ149M18.1; Lymphocyte antigen 95(activating NK receptor; NK p44). |
| 产品应用 | ELISA=1:5000-10000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD336 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 28 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > Cytotoxic Cells Signal Transduction > Adapters > Transmembrane |
| 亚基 | Interacts with TYROBP/DAP12. |
| 亚细胞定位 | Cell membrane; Single-pass type I membrane protein (Potential). |
| 组织特异性 | Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells. |
| 相似性 | Belongs to the natural cytotoxicity receptor (NCR) family. Contains 1 Ig-like (immunoglobulin-like) domain. |
| 功能 | Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | NCR2 (NKp44) is a member of the natural cytotoxicity receptor (NCR) family that is expressed on activated human NK cells. NCR2 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. Gene coding for NCR2 maps on human chromosome 6p21.1 |
| 应用 | 推荐稀释比例 |
| {ELISA} | {1:5000-10000} |
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文献和实验该产品被引用文献
[IF=8.713] Rimma Laufer Britva. et al. Involvement of ILC1-like innate lymphocytes in human autoimmunity, lessons from alopecia areata. ELIFE. 2023 Mar ICC Human
[IF=15.304] Yao Lei. et al. Phytochemical natural killer cells reprogram tumor microenvironment for potent immunotherapy of solid tumors. BIOMATERIALS. 2022 Jun;:121635 WB,IF,FCM Mouse
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NCR2 | NKp44/CD336 Rabbit pAb(bs-2420R)-50ul/100ul/200ul
￥1180 - 2800
