Sample:
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Kidney (Mouse) Lysate at 40 ug
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Primary: Anti-MYH9 (bs-9610R) at 1/300 dilution
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Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
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Predicted band size: 226 kD
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Observed band size: 226 kD
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- ￥1180 - 2800
- Bioss
- bs-9610R
- 2026年10月13日
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50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-9610R |
| 英文名称 | MYH9 Rabbit pAb |
| 中文名称 | 肌球蛋白重链9抗体 |
| 英文别名 | non-muscle Myosin IIA; Myosin heavy polypeptide 9 non muscle; Myosin-9; Myosin9; Myosin 9; Alternative namesnon-muscle IIa; type A; Cellular myosin heavy chain; Cellular myosin heavy chain type A; DFNA 17; DFNA17; EPSTS; FTNS; MHA; MYH 2A; MYH 9; MYH9_HUMAN; MYHas8; MYHas8; MyHC 2A; MyHC-Iia; MyHC-Iia; MYHSA 2; MYHSA2; MYHSA2; Myosin 9; Myosin heavy chain 9; Myosin heavy chain 9 non muscle; Myosin heavy chain; Myosin heavy chain non muscle Iia; Myosin heavy chain nonmuscle Iia; myosin heavy polypeptide 2; NMHC II A; NMMHC A; NMMHC II a; NMMHC II-a; NMMHC IIA; NMMHC-A; NMMHC-IIA; NMMHCA; Non muscle myosin heavy chain A; Non muscle myosin heavy chain; Non muscle myosin heavy chain II A; Non muscle myosin heavy polypeptide 9; Non-muscle myosin heavy chain A; Non-muscle myosin heavy chain IIa; Nonmuscle myosin heavy chain A. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Pig, Cow) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MYH9 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 226 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Cytoskeleton / ECM > Cytoskeleton > Motor Proteins > Myosin |
| 亚基 | Interacts with PDLIM2. Interacts with SLC6A4. Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Interacts with RASIP1. Interacts with DDR1. Interacts with SVIL and HTRA3. |
| 亚细胞定位 | Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. |
| 组织特异性 | In the kidney, expressed in the glomeruli. Also expressed in leukocytes. |
| 翻译后修饰 | ISGylated. |
| 相似性 | Contains 1 IQ domain. Contains 1 myosin head-like domain. |
| 功能 | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.Defects in MYH9 are the cause of May-Hegglin anomaly (MHA) . MHA is an autosomal dominant macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukokyte inclusions appearing as highly parallel paracrystalline bodies. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF=8.469] Que, Tianshi. et al. HMGA1 stimulates MYH9-dependent ubiquitination of GSK-3β via PI3K/Akt/c-Jun signaling to promote malignant progression and chemoresistance in gliomas. Cell Death Dis. 2021 Dec;12(12):1-12 WB,IF Human
[IF=8.2] Chun Huang. et al. Whole-transcriptome analysis of longissimus dorsi muscle in cattle-yaks reveals the regulatory functions of ADAMTS6 gene in myoblasts. INT J BIOL MACROMOL. 2024 Mar;262:129985 WB Mouse
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MYH9 | NMMHC-IIA Rabbit pAb(bs-9610R)-50ul/100ul/200ul
￥1180 - 2800
