CCR1 | CD191 Rabbit pAb(bs-1169R)-50ul/100ul/200ul产品图
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CCR1 | CD191 Rabbit pAb(bs-116

9R)-50ul/100ul/200ul
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  • ￥1180 - 2800
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  • bs-1169R
  • 2026年10月13日
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    北京博奥森生物技术有限公司
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      50ul/100ul/200ul

    规格：50ul产品价格：￥1180.0
    规格：100ul产品价格：￥1980.0
    规格：200ul产品价格：￥2800.0
    产品编号bs-1169R
    英文名称CCR-1/CD191 Rabbit pAb
    中文名称细胞表面趋化因子受体1抗体
    英文别名CC chemokine receptor 1; A630091E18Rik; CC-CKR-11; CCBP2; CCR10; CCR11; CCRL1; CCX-CKR; CCX-CKR1; CKR-11; Cmkbrl1; LOC684092; LOC685243; PPR1; VSHK1; C C chemokine receptor type 1; C C CKR 1; CC CKR 1; CCR 1; CD 191; CD191; CD191; Chemokine(C-C motif) receptor 1; Chemokine C C motif receptor 1; CKR 1; CKR1; CMKBR 1; CMKBR1; CMKR 1; CMKR1; HM145; LD78 receptor; Macrophage inflammatory protein 1 alpha/Rantes receptor; Macrophage inflammatory protein 1 alpha receptor; MIP 1alpha R; Mip-1a-R; MIP1aR; RANTES R; RANTES receptor; SCYAR1; CCR1_HUMAN; C-C chemokine receptor type 1; C-C CKR-1; CC-CKR-1; Short=CCR-1; CCR1; LD78 receptor; MIP-1alpha-R; RANTES-R; CD191.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human (Mouse, Rat)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CCR-1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量40 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Innate Immunity > Chemokines > Beta Chemokine Rec. (CCR)

    Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus

    亚基Interacts with CREB3.
    亚细胞定位Cell membrane; Multi-pass membrane protein.
    组织特异性Widely expressed in different hematopoietic cells.
    相似性Belongs to the G-protein coupled receptor 1 family.
    功能Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料bs-1169P is a synthetic peptide derived from human CCR-1. This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: human gastric carcinoma; 4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    _x000D_ Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    _x000D_ Incubation: Anti-CCR1 Polyclonal Antibody, Unconjugated(bs-1169R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    _x000D_

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    图标文献和实验
    该产品被引用文献

    [IF=5.4] Wangxia Peng. et al. Network pharmacology combines machine learning, molecular simulation dynamics and experimental validation to explore the mechanism of acetylbinankadsurin a in the treatment of liver fibrosis. J ETHNOPHARMACOL. 2023 Dec;:117682 WB,IF Human

    [IF=3.8] Wu Zhenyu. et al. Candesartan Mitigates Perioperative Neurocognitive Disorders by Modulating Hypertension-Linked Neuroinflammatory Factor. NEUROCHEM RES. 2025 Aug;50(4):1-22 WB Mouse

    [IF=3] Ming Chen. et al. Oxymatrine alleviates NSAID-associated small bowel mucosal injury by regulating MIP-1/CCR1 signalling and gut microbiota. J PHARMACOL SCI. 2024 Nov;156:149 IHC Rat

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    CCR1 | CD191 Rabbit pAb(bs-1169R)-50ul/100ul/200ul
    ￥1180 - 2800